Department of Veterans Affairs

January 10, 2020

Bone matrix changes during aging

Changes to the bone matrix that occur during aging may point to novel targets for treating osteoporosis.

By Leigh MacMillan
January 10, 2020

Structural views of a C. diff toxin

D. Borden Lacy and colleagues used cryo-electron microscopy to define the structure of a C. diff toxin, providing a framework for the design of novel therapeutics.

By Leigh MacMillan
November 5, 2019

Endotoxin shock protector

A novel tool developed by Vanderbilt scientists protects animals from endotoxin shock and can be used for mechanistic analyses of inflammation due to microbial and other insults.

By Bill Snyder
October 31, 2019

Acute kidney injury recovery time impacts future risk

Interventions that impact the timing of recovery following acute injury may improve future outcomes for patients.

By Danielle Kopke
3d rendering white blood cells with red blood cells
October 8, 2019

A new regulator of B cell development

New findings establish a role for the pro-inflammatory molecule IL-33 in the early development of antibody-producing B cells.

By Leigh MacMillan
October 3, 2019

A step toward gastric cancer

New research findings provide insight into the detrimental events that develop in response to H. pylori infection.

By Sanjay Mishra
October 3, 2019

Diabetes drug study explores cardiovascular risks for patients with kidney disease

An observational study using medical record information from nearly 50,000 U.S. military veterans sheds new light on which drugs are best for patients with Type 2 diabetes and one of its common complications, kidney disease.
By Paul Govern
September 25, 2019

Study shines light on architecture of kidney disease

A study of 280,000 U.S. veterans, including 56,000 African Americans, has identified in greater detail than ever before the genetic architecture of kidney function and chronic kidney disease (CKD), according to researchers at Vanderbilt University Medical Center and their colleagues.
By Bill Snyder
August 12, 2019

Pancreatic cancer clue

Inflammation synergizes with a cell’s intrinsic genetic program to promote the development of pancreatic cancer.
By Niyati Vachharajani
July 25, 2019

Sex differences in kidney injury

Men are more susceptible to progressive kidney disease than women; new VUMC studies point to differences in the expression and activation of the EGF receptor.
By Kelsey Herbers
April 25, 2019

A new antibiotic’s mechanism of action

Vanderbilt investigators have characterized how a new first-in-class antibacterial drug works, which will guide the development of additional compounds that overcome antibacterial resistance.
By Leigh MacMillan
March 28, 2019

Cancer prevention drug also disables H. pylori bacterium

A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered.
By Leigh MacMillan
March 14, 2019

Reprogramming cells for kidney repair

Using gene transfer technologies to reprogram adult human kidney cells could lead to novel therapies for chronic kidney disease.
By Kelsey Herbers
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