estrogen

Sex-specific regulation of kidney signals

Links between estrogen signaling and sodium excretion by the kidney could help explain a reduced risk of hypertension in females versus males.

Estrogen, depression and menopause

A shift in emotional processing may help women adapt to lower estrogen after menopause —unless they have a history of major depressive disorder, Vanderbilt researchers have found.

The importance of estrogen cycles

Deborah Lannigan and colleagues identify a key regulator of the estrogen receptor and suggest that its downregulation by oral contraceptives may increase oxidative stress and DNA damage, a common cause of cancer.

Asthma’s androgen connection

New findings may explain why the prevalence of asthma is higher in women and suggest that testosterone derivatives may be useful for treating more severe types of asthma.

Block estrogen to treat lung disease

Based on findings from Vanderbilt investigators and others, clinical trials of estrogen inhibition for pulmonary arterial hypertension have recently been approved and funded by the National Institutes of Health.

Cancer drug enhances cognition

The breast cancer drug tamoxifen improves cognitive performance in post-menopausal women.