Vanderbilt scientists have discovered that a certain enzyme plays a crucial role in preventing obesity-related cardiac dysfunction.

The hormone leptin regulates glucose balance, but not fat stores, in zebrafish.

Engineered bacteria that produce a therapeutic compound in the gut prevent obesity in mice, Vanderbilt University investigators have discovered.

Gaining and losing weight during “yo-yo dieting” may contribute to an exaggerated immune response in fat tissue that increases metabolic dysfunction more than steady weight gain alone.

A genetic variant may help keep an individual’s “good” cholesterol in check.

An obesity-associated genetic variation makes fatty food more rewarding yet less satisfying, new research in mice suggests.