hypoxia

December 14, 2020

Polymer protection for heart muscle

Vanderbilt researchers demonstrate that the polymer P188 has promise as a therapy to prevent reperfusion injury — the cellular damage that occurs when blood flow returns after an ischemic event like a heart attack.

By Leigh MacMillan
close up of blood vessels
October 15, 2020

Brain blood vessel response to hypoxia

The brain’s response to low oxygen — growth and remodeling of blood vessels — involves certain cell types and molecular pathways, Vanderbilt researchers have discovered.

By Leigh MacMillan
April 25, 2019

Low oxygen and antibody responses

Mark Boothby and colleagues are exploring the factors that contribute to antibody production and quality, which are key to our defense against pathogens and response to vaccines.

By Leigh MacMillan
Oxygen on periodic table
August 11, 2016

Study explores low oxygen’s impact on antibody quality

Hypoxia (lack of enough oxygen) is bad for the body as a whole, but in the neighborhood where infection-fighting antibodies arise, may be important for keeping proper order.

By Bill Snyder
February 6, 2013

Linking oxygen, iron and red blood cells

The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance.

By Leigh MacMillan
June 28, 2012

Low oxygen could protect sick kidneys

Low oxygen – and the activation of factors that respond to this situation – may be protective in chronic kidney disease.

By Leigh MacMillan