The protein SARM appears to protect cells from inflammation-driven death by stabilizing the nuclear laminin scaffold.

The factor STAT6 appears to play a role in the pathogenesis of an inflammatory bowel disease, suggesting it may be a promising target for new treatments.

Vanderbilt investigators report new insights to the workings of calprotectin, an immune system protein that “starves” bacterial pathogens of the metal nutrients they require.

In a wide-ranging lecture that moved from plants to nematode worms to human leukemia, Nobel laureate Andrew Fire, Ph.D., outlined his vision for a genomics-based understanding of how organisms respond to novel information.