insulin resistance

August 25, 2022

Inflammatory driver of obesity

Blocking the EGF receptor signaling pathway in immune system macrophages represents a new target for improving insulin resistance in people with obesity.

By Sarah E. Glass
Cholesterol
November 8, 2018

Obesity negates beneficial drug effects

A drug that improves levels of “good” cholesterol may not be beneficial for obese individuals, Vanderbilt researchers have discovered.

By VUMC News and Communications
Insulin in vials
October 11, 2018

Insulin accelerant

It’s possible to increase the permeability of blood vessels and accelerate insulin action in muscle, Vanderbilt researchers have discovered.

By Laura Daniel
Insulin in vials
January 25, 2018

Study may point to new ways to reverse insulin resistance

Researchers at Vanderbilt University have discovered how insulin crosses the capillary endothelium to exit blood vessels and stimulate skeletal muscle cells — a major finding that may lead to new ways to reverse insulin resistance, a hallmark of type 2 diabetes.

By Bill Snyder
Insulin in vials
May 11, 2017

EETs contribute to insulin sensitivity

Interventions that increase circulating levels of compounds called EETs may improve insulin sensitivity and treat hypertension.

By Leigh MacMillan
lungs
April 13, 2017

Clue to pulmonary hypertension

Vanderbilt investigators have studied the relationship between race, cardiometabolic traits and pulmonary hypertension.

By Bill Snyder
November 18, 2015

Fighting type 2 diabetes with FGF1

The growth factor FGF1 induces the growth of new insulin-producing beta cells and may help treat type 2 diabetes.
By VUMC News and Communications
September 8, 2015

Immune cells and obesity

Understanding how macrophage immune cells accumulate in fat tissue and contribute to the pathology of obesity could lead to the development of novel therapeutics for metabolic disorders.
By Leigh MacMillan
February 20, 2015

Tiny model of diabetes

Vanderbilt University researchers have created a zebrafish model of skeletal muscle insulin resistance that could help improve diabetes treatment.
By Bill Snyder