A new genetic model has generated new strategies for promoting tolerance to transplants – and improving long-term transplant outcomes – in the background of autoimmune disease.
The factor FoxM1 increases the proliferation and function of insulin-producing beta cells, making it an attractive therapeutic target for diabetes.
New findings suggest that it might be possible to treat diabetes by regenerating insulin-producing beta cells in the pancreas.
Vanderbilt researchers describe a new technique for identifying factors that stimulate the proliferation of pancreatic beta cells – factors that might offer therapeutic options for diabetes.
Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.
Adult cells in the pancreas can return to a less mature state – and then become a different cell type, like the beta cells that secrete insulin.
Accessibility Tools