Journal of Clinical Investigation Archive — Page 1 of 4
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July 8, 2021
Nature’s “recycler” could reduce heart disease risk: study
Researchers at Vanderbilt University Medical Center have identified potential new targets for the prevention of atherosclerosis through the enhancement of autophagy, a natural process for recycling damaged cellular material. -
April 1, 2021
Breast cancer cells ‘steal’ nutrients from immune cells: study
Triple-negative breast cancer cells engage in a “glutamine steal” — outcompeting T cells for the nutrient glutamine and impairing their ability to kill tumor cells, Vanderbilt researchers have discovered. -
March 25, 2021
Team studies new use for pulmonary hypertension drug
An FDA-approved medication enhances the function of T regulatory cells (Treg), a class of immune cells that restrains the immune response, Vanderbilt investigators have discovered. -
February 20, 2020
Post-transplant diabetes may be reversible: study
Post-transplantation diabetes mellitus (PTDM), a common complication of immunosuppressive drugs that are given to prevent transplant rejection, may be reversible and at least partially preventable, researchers at VUMC report. -
January 29, 2020
Study links neural circuit with impaired social function
Stimulating neural activity between the amygdala and the nucleus accumbens — a brain region associated with pleasure — impairs social function even though mice find the stimulation rewarding, a new study published by Vanderbilt researchers reports. -
July 24, 2019
Defective transporter linked to autism
A first-of-its-kind mouse model may help reveal mechanistic underpinnings for the altered behaviors of autism spectrum disorder. -
May 25, 2017
Study reveals role for stem cells in chronic lung diseases
A novel population of lung stem cells plays an important role in regulating the pulmonary microvasculature — the network of tiny blood vessels where oxygen and carbon dioxide exchange takes place.