Molecular Physiology & Biophysics

puzzel pieces, autism
January 29, 2015

Altered dopamine signaling may offer a clue to autism

Newly discovered genetic variations linked to autism spectrum disorder (ASD) disrupt the function of the dopamine transporter, suggesting that altered dopamine signaling contributes to this common developmental condition, according to a Vanderbilt University-led research team.

By Bill Snyder
obesity or overweight belly
January 22, 2015

New signaling pathway provides clues to obesity

A Vanderbilt University-led research team has discovered a molecular “rheostat” in the brain’s appetite control center that may provide new insights into obesity, which is at epidemic levels in this country.

By Bill Snyder
October 9, 2014

Neuert receives New Innovator Award from NIH

Vanderbilt University biophysicist Gregor Neuert, Ph.D., M.Eng., is among 50 recipients of the 2014 National Institutes of Health (NIH) Director’s New Innovator Award. Each award provides up to $1.5 million in direct research support over five years.

By Bill Snyder
Cholesterol
October 2, 2014

Team spots key regulator for cholesterol production

A Vanderbilt University-led research team has discovered a “master regulator” for cholesterol production and transport in the liver — a tiny piece of RNA called microRNA-223.

By Bill Snyder
colorful x-ray of brain
August 14, 2014

Team takes 4-D look at brain receptor’s role

Reporting last week in the journal Cell, researchers from Oregon Health and Science University, Harvard Medical School and Vanderbilt University describe the first “four-dimensional” picture of a brain receptor that plays a key role in learning and memory.

By Bill Snyder
hamburger and fries
June 2, 2014

Vanderbilt study supports notion ‘You are what you eat’

An international research group led by Vanderbilt University scientists has shown for the first time that a lipid, or fat molecule, can regulate “psychostimulant” behaviors by interacting with a brain protein.

By Bill Snyder
May 14, 2014

CaMKII enhances insulin secretion

The protein CaMKII acts as a calcium sensor in a positive feedback pathway that enhances glucose-stimulated insulin secretion.
By VUMC News and Communications
October 16, 2013

Relaxin combats insulin resistance

The hormone relaxin may offer a novel approach for treating diet-induced insulin resistance.
By Leigh MacMillan
October 3, 2013

Intracellular receptor expert set for next Discovery Lecture

Keith Yamamoto, Ph.D., an international leader in the study of signaling and gene regulation by intracellular receptors, will deliver the next Flexner Discovery Lecture on Thursday, Oct. 10.
By Leigh MacMillan
June 20, 2013

Disease linked to cell traffic jams

Diseases associated with mutations and changes in expression of the protein caveolin may result from faulty trafficking of the protein to the cell surface.
By Leigh MacMillan
April 25, 2013

Food variety drives overeating in mouse model of obesity syndrome

Dietary variety – not high-fat or sugary foods – appears to stimulate overeating in a mouse model of an inherited obesity syndrome.
By Bill Snyder
April 18, 2013

UT Southwestern’s Brown set to deliver Flexner Discovery Lecture

Nobel laureate Michael Brown, M.D., whose research paved the way for the development of cholesterol-lowering statin drugs, will deliver the next Flexner Discovery Lecture on Thursday, April 25.
By Leigh MacMillan
February 11, 2013

VU, GlaxoSmithKline team to develop novel treatments for severe obesity

Vanderbilt University has signed a collaboration agreement with GlaxoSmithKline (GSK) for the discovery, development and commercialization of novel therapies for severe obesity.
By Bill Snyder
1 2 3 4 5