NCATS

April 20, 2020

Damage, disruption, delirium

New findings suggest that treatments that decrease oxidative damage might help with postoperative delirium that occurs in up to 30% of cardiac surgery patients.

By Paul Govern
April 16, 2020

Transporter’s role in gut barrier

A disease-associated mutation in a transporter protein impairs gut barrier function, leading to gastrointestinal disease and chronic infections.

By Leigh MacMillan
March 19, 2020

Race, hormones and diabetes risk

Variation in the levels of hormones called natriuretic peptides may contribute to racial differences in susceptibility to diabetes, suggesting that this hormone system may be a target for reducing risk of the disease.

By VUMC News and Communications
February 10, 2020

Imaging breast cancer cell size

A noninvasive MRI approach assesses breast tumor cell size and could be a useful way to evaluate early response to neoadjuvant therapy.

By Leigh MacMillan
December 16, 2019

Protein dynamics in the beating heart

To study the dynamics of structural proteins in the heart, Vanderbilt investigators generated a cellular tool they expect will be useful for screening drugs that affect heart muscle contraction.

By Leigh MacMillan
November 19, 2019

Getting the goods on obesity

Obesity and two post-operative complications linked with it have associated genetic variants in common, suggesting that obesity may be the culprit.

By Paul Govern
November 14, 2019

RSV transmission in the Middle East

Understanding how RSV is transmitted, which strains dominate and how new strains emerge around the globe will guide better vaccine and anti-viral drug design.
By Laura Powell
October 8, 2019

A new regulator of B cell development

New findings establish a role for the pro-inflammatory molecule IL-33 in the early development of antibody-producing B cells.
By Leigh MacMillan
October 3, 2019

Study: personalized decision support affects intensive care

For patients in pediatric intensive care who are at high risk for acute kidney injury (AKI), giving clinicians automated decision support during the electronic order entry process increased the rate of blood testing for AKI by 9%.
By Paul Govern
September 24, 2019

Treating C. diff: new purpose for an old drug?

An inexpensive generic drug once used to prevent gastrointestinal ulcers in people taking daily NSAIDs protects against C. diff infection in mice.
By Paul Govern
June 24, 2019

Early detection of schizophrenia

Inhibited temperament — a tendency to respond to novelty with wariness, fear or caution — may be a risk factor for schizophrenia that could be targeted for preventative interventions.
By Leigh MacMillan
March 28, 2019

Cardiac dysfunction in DMD

The protein MMP7 is elevated in blood from patients with Duchenne muscular dystrophy who have cardiac dysfunction, suggesting that it may be a biomarker for heart disease severity.
By Leigh MacMillan
February 28, 2019

Personalized pain management

Understanding how natural brain chemicals with pain-relieving properties interact with administered opioids may guide personalized approaches for pain management.
By Niyati Vachharajani
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