New England Journal of Medicine

Combination therapy improves small-cell lung cancer survival

Patients with stage IV small-cell lung cancer lived longer when given the immunotherapy atezolizumab with chemotherapy, setting the stage for what could become the first new treatment approved in decades for this particularly aggressive form of lung cancer.

Antipsychotics ineffective for treating ICU delirium: study

Critically ill patients are not benefiting from antipsychotic medications that have been used to treat delirium in intensive care units (ICUs) for more than four decades, according to a study released today in the New England Journal of Medicine.

Time window extended for some stroke surgeries

New research indicates the time window for a thrombectomy following a stroke is longer than previously thought, but how soon the surgery occurs still matters.

Saline use on decline at Vanderbilt following landmark studies

Vanderbilt University Medical Center is encouraging its medical providers to stop using saline as intravenous fluid therapy for most patients, a change provoked by two companion landmark studies released Feb. 27 that are anticipated to improve survival and decrease kidney complications.

Team finds stem cell transplant improves scleroderma survival

A new clinical trial by investigators at Vanderbilt University Medical Center (VUMC) and other leading medical centers found that an intensive transplant treatment using the patient’s own stem cells can improve survival and quality of life for patients with advanced scleroderma.

NEJM Catalyst forum addresses mental, behavioral and social health determinants

Healthcare is more than diagnosing and treating disease. To truly improve health outcomes for individuals and communities, the mental, behavioral and social determinants of health must be fully integrated with physical factors at all levels of the healthcare system.

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