New findings suggest that misfolded proteins accumulate in the heart atria, particularly in patients with hypertension, and may contribute to atrial heart disease.
A newly identified “atheroprotective” gene is a tool for exploring plaque pathophysiology and may be a good target for therapies to slow atherosclerosis progression.
Vanderbilt researchers have discovered a new target for the prevention of atherosclerotic plaque development and cardiovascular disease.
An overactive stress response contributes to the development of insulin resistance in obese individuals, and blocking it may be therapeutically beneficial.
A cell-penetrating peptide developed at Vanderbilt blocks the signaling pathways that lead to lethal shock caused by bacterial infection.
Vanderbilt researchers have discovered that certain immune cells contribute to the development of hypertension, suggesting novel targets for treating the disease.