NHLBI

April 12, 2013

Lung damage protector

Targeting repair pathways in the lung’s air sacs may be a valuable therapeutic direction for pulmonary fibrosis – the scarring of lung tissue.

By Leigh MacMillan
April 11, 2013

Leukemia culprit’s cellular actions

Overexpression of a gene that is a common culprit in leukemia induces stem cell-like features in T cells, which may enable the cells to become cancerous.

By Leigh MacMillan
March 28, 2013

Acetaminophen: protective in sepsis?

In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen.

By Leigh MacMillan
March 18, 2013

IRF6 on the tip of tongue development

The factor IRF6 plays important roles in the development of the tongue.

By Leigh MacMillan
March 6, 2013

Tick-tock – predicting menopause

An ultrasound count of potentially egg-producing follicles could predict the timing of menopause.

By Leigh MacMillan
February 21, 2013

Antibacterial protein’s molecular workings revealed

Vanderbilt investigators report new insights to the workings of calprotectin, an immune system protein that “starves” bacterial pathogens of the metal nutrients they require.

By Leigh MacMillan
February 14, 2013

Cell connections key in valve disease

A protein that connects cells together participates in the calcification that occurs in heart valve disease.
By Leigh MacMillan
February 1, 2013

Cell source of heart’s blood vessels

An unexpected group of cells generates the coronary arteries and may be useful for regeneration therapies following injury to the heart.
By Leigh MacMillan
January 21, 2013

HDL cholesterol impaired in kidney disease

HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk.
By Leigh MacMillan
December 26, 2012

Preventing hardened heart valves

Blocking a serotonin receptor may provide a novel therapy for heart valve disease.
By Leigh MacMillan
December 10, 2012

Genetic clues to lung scarring

A rare genetic syndrome provides new clues to lung scarring (pulmonary fibrosis), a potentially deadly consequence of many lung diseases.
By VUMC News and Communications
November 16, 2012

Green tea for failing hearts?

The main antioxidant compound in green tea increases contractile force in isolated heart cells, suggesting it may be useful in heart failure.
By Leigh MacMillan
November 15, 2012

Grant to bolster care of ventilated ICU patients

Vanderbilt University Medical Center investigators have received a $2.8 million grant from the National Heart, Lung, and Blood Institute (NHLBI) to continue studying ways to improve sedation management for intensive care unit patients who are on mechanical ventilators.
By Jill Clendening
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