Study merges big data and zebrafish biology to reveal mechanisms of human disease

In a series of studies that volleyed between large databases and research in zebrafish, Vanderbilt investigators have discovered a link between vascular biology and eye disease.

Targeting tumor “supply lines”

A metabolic enzyme plays a crucial role in vascular development and may be a good target for cancer therapies.

Gene interactions and cavities

Vanderbilt researchers used existing genome-wide association study datasets to identify gene interactions that contribute to tooth decay.

IRF6 on the tip of tongue development

The factor IRF6 plays important roles in the development of the tongue.