NIDDK

Grant to spur study of ‘brown fat’s’ metabolic mysteries

Vanderbilt researchers have received a $2.15 million grant to study the amount and activity of “brown fat” in adults, with the aim of understanding its role in metabolic disease and identifying new therapeutic targets.

HIV cell

New strategy to combat HIV

Inhibitors of the enzyme phospholipase D1 suppress the replication of HIV-1, Vanderbilt investigators have discovered.

A “CRISPR” way to study disease

Using revolutionary CRISPR technology, Vanderbilt investigators have developed a fast and simple method to simultaneously turn off multiple genes in order to study complex diseases.

Team tracks how kidney responds to blood pressure meds

Changes in the kidney can limit the blood pressure-lowering effects of thiazide diuretics, a new study reports.

Boosting beta cells in diabetes

New findings suggest that it might be possible to treat diabetes by regenerating insulin-producing beta cells in the pancreas.

Surprising finding in the kidney

TGF-beta signaling in the kidney was thought to be a target for reducing renal fibrosis, but Vanderbilt researchers report that fibrosis still occurs in the absence of TGF-beta signaling.

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