Larry Marnett and colleagues have explored the role of two enzymes in metabolizing molecules associated with cell proliferation, inflammatory processes and neurological diseases.

Treatments for common skin conditions such as atopic dermatitis may be improved by understanding the enzymes responsible for forming the skin’s water-tight barrier.

Structural details about a protein involved in the repair of damaged DNA provide insight into xeroderma pigmentosum disorders, which are characterized by increased risk for skin cancer.

Vanderbilt investigators have developed a new method for measuring oxidative stress in human tumors, which provides insight into cancer development.

Structural details of a protein that removes DNA lesions shed light on fundamental mechanisms of DNA repair.

A new microfluidic device containing human cells that faithfully mimics the behavior of the blood-brain barrier is providing new insights into brain inflammation, the silent killer.

A compound found in buckwheat seeds extends the lifespan of worms, Vanderbilt investigators have discovered.