NIEHS

Eric Skaar, PhD, MPH, Hualiang Pi, PhD, and colleagues are studying a regulatory factor in the bacterium that causes the disease anthrax.
April 7, 2022

Study advances understanding of bacterial bioterrorism agent

Vanderbilt researchers have identified a critical regulatory factor in the bacterium that causes the disease anthrax and has been used as a biological weapon.

By Leigh MacMillan
January 13, 2022

Salmonella overcomes host resistance

The invading pathogen Salmonella, a common cause of food poisoning, can change its metabolism to overcome host resistance to its colonization.

By Leigh MacMillan
June 18, 2020

Probing DNA damage repair

After discovering a new mechanism for DNA damage repair last year, Vanderbilt biochemists now provide direct evidence for how it works.

By Leigh MacMillan
May 14, 2020

The adaptable anthrax bacterium

Vanderbilt researchers discover how anthrax bacterium defends itself against structural damage and resists the toxicity of the antimicrobial drug targocil.

By Leigh MacMillan
David Cortez, PhD, left, Petria Thompson, Katherine Amidon, Brandt Eichman, PhD, and colleagues are studying how a DNA repair pathway protein shields sites of damage to avoid mutations.
July 25, 2019

Team’s study reveals details of new DNA repair pathway

Investigators have discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity.

By Leigh MacMillan
June 12, 2019

Steroid binding to metabolic enzyme

Understanding how a steroid-metabolizing enzyme binds to its substrates may aid in designing drugs to treat sexual dysfunction as well as prostate cancer.

By Bill Snyder
February 14, 2019

The yin and yang of cell signaling

Larry Marnett and colleagues have explored the role of two enzymes in metabolizing molecules associated with cell proliferation, inflammatory processes and neurological diseases.
By Sanjay Mishra
April 19, 2018

How the skin protects

Treatments for common skin conditions such as atopic dermatitis may be improved by understanding the enzymes responsible for forming the skin’s water-tight barrier.
By Sanjay Mishra
December 5, 2017

DNA damage repair: molecular insights

Structural details about a protein involved in the repair of damaged DNA provide insight into xeroderma pigmentosum disorders, which are characterized by increased risk for skin cancer.
By VUMC News and Communications
May 18, 2017

Oxidative stress in tumors

Vanderbilt investigators have developed a new method for measuring oxidative stress in human tumors, which provides insight into cancer development.
By Sanjay Mishra
April 14, 2017

A new mode of DNA repair

Structural details of a protein that removes DNA lesions shed light on fundamental mechanisms of DNA repair.
By Leigh MacMillan
December 6, 2016

Blood-brain barrier on a chip sheds new light on “silent killer”

A new microfluidic device containing human cells that faithfully mimics the behavior of the blood-brain barrier is providing new insights into brain inflammation, the silent killer.
By VUMC News and Communications
October 20, 2016

Study finds natural compound extends lifespan of worms

A compound found in buckwheat seeds extends the lifespan of worms, Vanderbilt investigators have discovered.
By Leigh MacMillan
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