NIGMS

June 12, 2017

Repriming replication roadblocks

New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away.

By Sanjay Mishra
elderly Asian mother and adult daughter
April 27, 2017

Protein structure may aid in treating Alzheimer’s disease

A new protein structure may guide the development of Alzheimer’s therapeutics.

By Leigh MacMillan
March 31, 2017

A molecular clue to longevity

In budding yeast, accumulation of a certain type of RNA in the nucleus increased life span, offering a new clue to longevity.

By Laura Daniel
February 23, 2017

A target to heal tiny lungs

The protein beta-catenin may be a good target for therapies to treat lung disease that is a common complication of preterm birth.

By Leigh MacMillan
February 8, 2017

Pathology of septic shock

The signaling molecule IL-15 promotes septic shock, a life-threatening condition involving organ injury caused by infection.

By Leigh MacMillan
bacteria microbiome
February 3, 2017

Bacterial signaling systems

Vanderbilt researchers have identified a unique example of communication between bacterial signaling systems, which may have relevance for antibiotic resistance.

By Leigh MacMillan
February 2, 2017

New target for chronic infection

An enzyme in macrophage immune cells may be a good target for treating chronic infections, Vanderbilt researchers have discovered.
By VUMC News and Communications
January 20, 2017

Improving vaccine formulations

The compound MPLA is an attractive vaccine component, designed to elicit a robust immune response.
By Sanjay Mishra
December 12, 2016

Single-cell analysis of solid tumors

A new method will make it possible to study solid tumors and healthy tissues using mass cytometry.
By Heather McCartney
December 8, 2016

Making human beta cells reproduce

A new method developed at Vanderbilt will speed the search for potential therapeutics for diabetes: compounds that stimulate the replication of insulin-producing beta cells.
By VUMC News and Communications
December 8, 2016

Plasmin prevents muscle ‘hardening’ after injury: study

Vanderbilt researchers have made the surprising discovery that the protease plasmin, known for its clot-busting role in the blood, protects soft tissue from turning to bone after severe injuries and certain orthopaedic surgeries.
By Leigh MacMillan
November 18, 2016

Targeting the “un-targetable”

A novel drug that targets the protein RSK blocked aggressive breast cancers from metastasizing in an animal model.
By VUMC News and Communications
November 17, 2016

Stem cells promote tolerance

Blood-forming stem cells play a role in immune tolerance and acceptance of organ transplants, Vanderbilt researchers have discovered.
By Leigh MacMillan
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