NIGMS

July 25, 2017

Altered metabolism and disease

Vanderbilt researchers report a structure of a human metabolic enzyme bound to its substrate 17alpha-hydroxyprogesterone.

By VUMC News and Communications
July 21, 2017

Probing the genetics of autoimmunity

Vanderbilt researchers have found that non-coding regions of the genome appear to contribute to the risk of autoimmune diseases and may represent attractive therapeutic targets.

By Leigh MacMillan
July 3, 2017

NOTCH1 role in heart development

The identification of a genetic culprit for hypoplastic left heart syndrome could lead to new treatments for the condition.

By VUMC News and Communications
June 29, 2017

Genetics of lung cancer survival

Vanderbilt investigators have conducted a first-of-its-kind genome-wide association study of lung cancer survival in African-Americans.

By Sanjay Mishra
June 12, 2017

Repriming replication roadblocks

New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away.

By Sanjay Mishra
elderly Asian mother and adult daughter
April 27, 2017

Protein structure may aid in treating Alzheimer’s disease

A new protein structure may guide the development of Alzheimer’s therapeutics.

By Leigh MacMillan
March 31, 2017

A molecular clue to longevity

In budding yeast, accumulation of a certain type of RNA in the nucleus increased life span, offering a new clue to longevity.
By Laura Daniel
February 23, 2017

A target to heal tiny lungs

The protein beta-catenin may be a good target for therapies to treat lung disease that is a common complication of preterm birth.
By Leigh MacMillan
February 8, 2017

Pathology of septic shock

The signaling molecule IL-15 promotes septic shock, a life-threatening condition involving organ injury caused by infection.
By Leigh MacMillan
February 3, 2017

Bacterial signaling systems

Vanderbilt researchers have identified a unique example of communication between bacterial signaling systems, which may have relevance for antibiotic resistance.
By Leigh MacMillan
February 2, 2017

New target for chronic infection

An enzyme in macrophage immune cells may be a good target for treating chronic infections, Vanderbilt researchers have discovered.
By VUMC News and Communications
January 20, 2017

Improving vaccine formulations

The compound MPLA is an attractive vaccine component, designed to elicit a robust immune response.
By Sanjay Mishra
December 12, 2016

Single-cell analysis of solid tumors

A new method will make it possible to study solid tumors and healthy tissues using mass cytometry.
By Heather McCartney
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