Vanderbilt investigators have discovered a class of compounds that inhibit a mediator of inflammation and autoimmune disorders, and that could pave the way for development of future therapies.

New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines.

Although drug addiction is classically studied in a neuron-centric way, Vanderbilt researchers have discovered that the immune system also plays a critical role.

Vanderbilt researchers report a structure of a human metabolic enzyme bound to its substrate 17alpha-hydroxyprogesterone.

Vanderbilt researchers have found that non-coding regions of the genome appear to contribute to the risk of autoimmune diseases and may represent attractive therapeutic targets.

The identification of a genetic culprit for hypoplastic left heart syndrome could lead to new treatments for the condition.

Vanderbilt investigators have conducted a first-of-its-kind genome-wide association study of lung cancer survival in African-Americans.