NIGMS Archive
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July 2, 2018
SMAD4 clue to colon cancer
Loss of a gene that is part of the TGF-beta signaling pathway increased inflammation in the colon and was observed in half of human colitis-associated cancers. -
June 28, 2018
New staph virulence factor
Jun. 28, 2018—The new factor, an enzyme involved in host-pathogen interactions, may be a viable target for treating staph infections. -
June 13, 2018
Novel infection fighter
A drug in use clinically to help make vaccines more effective may be a powerful new tool for fighting antibiotic-resistant infections. -
June 11, 2018
Confronting TB resistance
Vanderbilt researchers describe how certain tuberculosis treatments work and suggest these medications may overcome the threat of drug-resistant tuberculosis. -
June 8, 2018
A “public” target for HIV
Common sequences of antibodies against HIV may be key to developing a successful vaccine strategy for the virus. -
May 9, 2018
Putting the brakes on sepsis
An enzyme called PTEN reduces inflammatory signaling and mortality in sepsis, suggesting it may be a good therapeutic target for this life-threatening complication of infection. -
April 23, 2018
Toxin floats on lipid rafts
The bacterium H. pylori is a leading cause of stomach cancer, and Vanderbilt researchers are studying how one of its toxins gets into cells.