NIGMS Archive

February 14, 2019

The yin and yang of cell signaling

Larry Marnett and colleagues have explored the role of two enzymes in metabolizing molecules associated with cell proliferation, inflammatory processes and neurological diseases.

January 17, 2019

Signals from the “conveyor belt”

Vanderbilt researchers propose that cellular signaling pathways are amplified by a “conveyor belt” mechanism that exchanges active and inactive enzymes.

January 17, 2019

DNA’s on/off switch

DNA-binding “switches” represent a fundamentally new method of communication between DNA-processing enzymes, Vanderbilt researchers propose.

December 13, 2018

The exocyst dynamo

New methods have revealed details of vesicle trafficking in cells and are applicable to any protein complexes, potentially revolutionizing our understanding of cell dynamics.

November 29, 2018

Analyzing single-cell landscapes

Vanderbilt researchers have developed a new tool for quantifying data from single-cell studies.

Lymphocytes attacking cancer cell
November 8, 2018

Evading cell death

Stress granules that form in response to cellular stress help cancer cells survive and develop resistance to treatment.