NIGMS Archive — Page 12 of 20

Orange-and-white striped road barricade with two warning lights, accompanied by a traffic cone and a fallen construction barrel.
June 12, 2017

Repriming replication roadblocks

New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away.

elderly Asian mother and adult daughter
April 27, 2017

Protein structure may aid in treating Alzheimer’s disease

A new protein structure may guide the development of Alzheimer’s therapeutics.

A caregiver gently holds an older adult’s wrinkled hand; both hands wear rings, and the caregiver wears a wristwatch.
March 31, 2017

A molecular clue to longevity

In budding yeast, accumulation of a certain type of RNA in the nucleus increased life span, offering a new clue to longevity.

Newborn baby resting in a hospital incubator with monitoring electrodes attached to the chest, while an adult’s hand gently touches the baby’s head.
February 23, 2017

A target to heal tiny lungs

The protein beta-catenin may be a good target for therapies to treat lung disease that is a common complication of preterm birth.

3D-rendered illustration of red blood cells and smaller pale green and yellow spherical cells suspended against a dark red background.
February 8, 2017

Pathology of septic shock

The signaling molecule IL-15 promotes septic shock, a life-threatening condition involving organ injury caused by infection.

bacteria microbiome
February 3, 2017

Bacterial signaling systems

Vanderbilt researchers have identified a unique example of communication between bacterial signaling systems, which may have relevance for antibiotic resistance.