NIGMS Archive — Page 14 of 20

Multiple labeled blood collection tubes with purple caps arranged in a blue rack; several tubes display barcodes.
January 13, 2016

Platelet protein modification

Vanderbilt investigators have identified a new biomarker to assess platelet function.

blood cells
January 7, 2016

Immune tolerance in endothelial cells

Inducing “tolerance” to bacterial toxins in the endothelial cells that line blood vessels may offer a new approach for preventing the negative consequences of sepsis.

green traffic light
December 3, 2015

Microtubules act as cellular ‘rheostat’ to control insulin secretion

Microtubules — cellular “highways” that deliver cargo to the cell membrane for secretion — have a surprising role in pancreatic beta cells. Instead of facilitating glucose-stimulated insulin secretion, they limit it, a team of Vanderbilt investigators reported recently in Developmental Cell.

Close-up of a person applying ointment from a small white tube to a scraped, bruised knee.
October 16, 2015

Healing without scarring

Drugs that inhibit the Wnt signaling pathway can regenerate injured skin and may be useful in treating fibromatosis, degenerative joint disease and cancer.

Black-and-white yin-yang symbol with two contrasting comma-shaped halves and a dot in each half.
October 2, 2015

The yin and yang of COX-2

New findings add to the understanding of how the enzyme COX-2 works, which is critical to the development of COX-2-targeted anti-inflammatory drugs.

conceptual - glowing cell
October 1, 2015

Tolerating a transplant

A new genetic model has generated new strategies for promoting tolerance to transplants – and improving long-term transplant outcomes – in the background of autoimmune disease.