NIGMS Archive — Page 16 of 20

Fluorescence microscopy image of a cultured cell showing a dense network of turquoise microtubules, with their plus ends highlighted in red.
October 30, 2014

VU study reveals factor’s new role in cell division, migration

Vanderbilt University investigators have discovered a new molecular mechanism that regulates microtubule dynamics. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery.

Manual blood pressure monitor with a blue cuff, round pressure gauge, black inflation bulb, and attached stethoscope on a white background.
October 24, 2014

Immune cells’ role in hypertension

Vanderbilt researchers have discovered that certain immune cells contribute to the development of hypertension, suggesting novel targets for treating the disease.

Three-panel molecular structure diagram comparing membrane-protein conformations. The first two panels show translucent protein surfaces with colored helices labeled “Ex,” “In,” “EL4,” “Bundle,” “Scaffold,” and “Gates,” plus arrows, distances, and a 21° angle; the third shows overlaid ribbon structures with an RMSD scale from 0.16 to 15.6 Å.
October 23, 2014

New view of transporter dynamics

New insights to the workings of a protein that moves neurotransmitters across the nerve cell membrane could aid the design of more effective antidepressants.

Open orange prescription bottle lying on its side with numerous green-and-white capsules spilled onto a white surface.
October 15, 2014

Antibiotics, fetal vessel defect linked

Certain antibiotics increase the risk of a congenital heart disorder called patency of the ductus arteriosis.

October 14, 2014

Neuronal culprit in genetic disease

A particular neuronal cell population is involved in the pathogenesis of a rare neurological disorder, Vanderbilt researchers have discovered.

September 26, 2014

Biomarker for diabetic eye disease

A person’s mitochondrial gene “signature” could predict risk for diabetic retinopathy and guide early intervention strategies.