NIH Archive — Page 1 of 93

White disposable surgical mask labeled “COVID-19” on a light blue background.
February 22, 2024

NIH-funded trial to determine if immunomodulation can improve brain and cardiovascular dysfunction in Long COVID

Vanderbilt University Medical Center is working with scientists around the U.S. to launch the first Phase III, multicenter, placebo-controlled trial to determine the effect of immunomodulation on Long COVID.

Rows of labeled blood collection tubes with purple caps arranged in a plastic tray, with barcodes visible on several tubes.
February 1, 2024

A biomarker for early Type 2 diabetes

Genetic analyses suggest that branched chain amino acids may be a sensitive biomarker of early or subclinical Type 2 diabetes and could be used to identify risk and implement preventive measures.

Illustration of a large yellow cell surrounded by several smaller blue cells in a fluid-like environment, depicting immune-cell interactions.
January 16, 2024

Data haul improves immunotherapy response prediction

Vanderbilt biostatisticians have developed an immunotherapy response model that outperforms existing predictive models.

Abstract 3D illustration of computer programming code and glowing circuit-like interface graphics in blue, teal, pink, and orange.
January 2, 2024

Team uses COVID-19 to test automated acute disease profiling

An automated solution for creating phenotyping algorithms, PheNorm, worked well to identify symptomatic COVID-19 cases in electronic health records, suggesting that automation could speed high-throughput phenotyping of acute disease.

3D rendering of a dense, spiky pink-and-yellow spherical particle surrounded by numerous Y-shaped antibody-like molecules against a pale background.
December 29, 2023

Glucose metabolism influences B cell function

Glucose metabolism influences the qualities of activated, mature B cells — white blood cells that are required for antibody-mediated immune responses, Vanderbilt researchers discovered.

Mariana Byndloss, DVM, PhD, (left), graduate student Catherine Shelton, and their colleagues discovered that beneficial bacteria in the small intestines produce a compound that protects against obesity. (photo by Erin O. Smith)
December 8, 2023

Gut microbiota metabolite protects against obesity: Study

Vanderbilt researchers have discovered that beneficial bacteria in the small intestines produce a compound that protects against obesity.