NIH

September 10, 2020

Award supports integration of genomic data, electronic health records

Eric Gamazon, PhD, assistant professor of Medicine, has been awarded a $1.5 million grant from the National Human Genome Research Institute, part of the National Institutes of Health (NIH), to develop novel computational tools that integrate functional genomic data and electronic health records.

By Leigh MacMillan
pregnant belly
September 8, 2020

Fibroids and birth outcomes

Women with three or more uterine fibroids — non-cancerous growths — during pregnancy are more likely to have infants with reduced birthweight and may need additional surveillance.

By Leigh MacMillan
September 3, 2020

New clue to Alzheimer’s disease

Combining studies of genetically diverse mouse populations and human data led to the identification of a gene associated with cognitive decline and brain changes in Alzheimer’s disease.

By Bill Snyder
September 3, 2020

Assembling cell power plant machinery

Tina Iverson and colleagues provide a structural view into the assembly of a protein machine essential for cellular energy production.

By Leigh MacMillan
August 25, 2020

Blocking tumor ‘signals’ and ‘fuel’

Combining two drugs reduced colorectal cancer cell growth in vitro and in an animal model, suggesting the combination may be a promising treatment for patients.

By Leigh MacMillan
August 24, 2020

Land of plenty (of opioids)

Surgical patients are being given more opioids than they need for postsurgical pain management, raising the risk of addiction.

By Paul Govern
August 20, 2020

Salt, immune cells and hypertension

Excess dietary salt activates immune cells to induce inflammation and hypertension, supporting current recommendations for low sodium consumption.
By Leigh MacMillan
August 20, 2020

A “torque” for tumor blood vessels

Vanderbilt scientists have discovered a new target for normalizing tumor blood vessels to improve cancer immunotherapies.
By Bill Snyder
August 11, 2020

Risk marker for repeat sinus surgery

An inflammatory factor in mucus could be a biomarker of treatment-resistant chronic sinusitis used to determine which patients are at risk for repeat sinus surgery.
By Leigh MacMillan
August 6, 2020

ID of ‘stomach flu’ culprit

Identifying the norovirus genotypes associated with more severe infections in children could guide strain selection for candidate norovirus vaccines.
By Leigh MacMillan
August 6, 2020

The importance of estrogen cycles

Deborah Lannigan and colleagues identify a key regulator of the estrogen receptor and suggest that its downregulation by oral contraceptives may increase oxidative stress and DNA damage, a common cause of cancer.
By Sarah E. Glass
August 6, 2020

Appendix cancer survival in young patients varies by race: study

The first study of appendiceal cancer patterns and survival by race/ethnicity among patients younger than 50 in the U.S. showed survival disparities.
By Leigh MacMillan
July 28, 2020

Post-transplant complication

Vanderbilt researchers conducted the largest analysis to date of a heart complication in children following stem cell transplant. The findings may help guide screening practices to improve outcomes.
By Leigh MacMillan
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