NIH

June 20, 2019

Potential probe for early ovarian cancer

Larry Marnett and colleagues have developed what may become the first agent for targeted PET imaging of cancer tissues, such as ovarian cancer, that express high levels of the COX-1 enzyme.

By Anivarya Kumar
June 12, 2019

Steroid binding to metabolic enzyme

Understanding how a steroid-metabolizing enzyme binds to its substrates may aid in designing drugs to treat sexual dysfunction as well as prostate cancer.

By Bill Snyder
June 10, 2019

Cell-cell signals in developing heart

Scott Baldwin and colleagues have discovered early signaling events during heart development, findings that could guide cell replacement therapies for heart disease.

By Leigh MacMillan
June 6, 2019

Mouth microbes and colorectal cancer

Microbial species in the mouth could be playing a role in colorectal cancer development, according to new research from epidemiologists at VUMC.

By Leigh MacMillan
May 29, 2019

Study details regulation of a multi-drug transporter

P-glycoprotein distinguishes between chemicals that it will expel from a cell and inhibitors that block its action.

By Leigh MacMillan
May 16, 2019

Byndloss selected for NIH future research leaders conference

Mariana Byndloss, DVM, PhD, has been selected to participate in the Future Research Leaders Conference at the National Institutes of Health.

By Leigh MacMillan
May 9, 2019

Frog fungus fights back

Louise Rollins-Smith and colleagues are exploring how a deadly fungus counters the amphibian immune response and contributes to declining worldwide amphibian populations.
By Leigh MacMillan
May 9, 2019

Blueprint for rebuilding the heart

Young-Jae Nam and colleagues are discovering how to express specific factors in connective tissue cells to turn them into heart muscle cells.
By Anivarya Kumar
May 9, 2019

The dynamic basement

Vanderbilt scientists led by Andrea Page-McCaw have discovered a new way to analyze repair of basement membranes — important structural and functional components of tissues.
By Sanjay Mishra
April 25, 2019

A new antibiotic’s mechanism of action

Vanderbilt investigators have characterized how a new first-in-class antibacterial drug works, which will guide the development of additional compounds that overcome antibacterial resistance.
By Leigh MacMillan
April 25, 2019

Immune ‘pruning’ in schizophrenia

Ariel Deutch and colleagues have discovered that overactive brain immune cells during adolescence may contribute to schizophrenia.
By Bill Snyder
April 25, 2019

Receptor’s role in stopping H. pylori

The immune receptor NOD1 may be a prime target for preventing or treating H. pylori infections — the most significant risk factor for stomach cancer, Vanderbilt researchers have discovered.
By Niyati Vachharajani
April 25, 2019

Low oxygen and antibody responses

Mark Boothby and colleagues are exploring the factors that contribute to antibody production and quality, which are key to our defense against pathogens and response to vaccines.
By Leigh MacMillan
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