NIH

April 14, 2016

Switching breast cancer off

Signaling by a receptor that is overexpressed in aggressive forms of breast cancer has been linked to glutamine metabolism, suggesting new anti-cancer therapeutic targets.

By Marilyn Holt
April 5, 2016

Immune defenses in asthma

Vanderbilt researchers show that a certain factor negatively impacts the first-line responder cells in the lungs, providing one explanation for why patients with asthma are at greater risk for invasive bacterial disease.

By Leigh MacMillan
DNA sequence visualization
April 1, 2016

New role identified for p73 gene

The p73 gene is required for the generation of cilia – hair-like projections on cells – findings that could have implications for the study of lung diseases and sterility.

By VUMC News and Communications
March 31, 2016

Cancer prevention and poverty

A new epidemiological study supports smoking cessation and avoidance of sedentary lifestyle as cancer prevention measures.

By Paul Govern
March 23, 2016

Readmission prediction face-off

Using patients’ health records to assess preparedness for hospital discharge is more effective at predicting readmission or death than commonly used questionnaires.

By Paul Govern
March 21, 2016

Putting schizophrenia to bed

A new compound developed at Vanderbilt treats multiple symptoms of schizophrenia in an animal model, without causing sedation.

By VUMC News and Communications
March 17, 2016

ROCKs and cancer invasion

The rigidity of the microenvironment around cancer cells drives invasive behavior through distinct ROCK signaling pathways, which could guide the development of specific anti-invasive therapies.
By Sanjay Mishra
March 17, 2016

Study suggests cancer’s ‘clock’ can be rewound

Researchers at Vanderbilt University Medical Center have “turned back the clock” in a mouse model of metaplasia — precancerous stomach lesions — raising hopes that gastric cancer, a worldwide scourge that’s rising in the United States, can be prevented.
By Bill Snyder
March 9, 2016

Eye of a cytokine storm

A new animal model can be used to “dissect” the inflammatory response to infection.
By Bill Snyder
March 8, 2016

Fat hormone’s role in zebrafish

The hormone leptin regulates glucose balance, but not fat stores, in zebrafish.
By Leigh MacMillan
March 7, 2016

A clue to cell cleavage

Actin and microtubule cytoskeletons are coordinated during cytokinesis – the process that separates one cell into two and is linked to events underlying cancer.
By Sanjay Mishra
March 3, 2016

Melanoma response to immune therapy

Melanoma-specific expression of a certain protein identifies tumors that are more responsive to an immune therapy.
By Leigh MacMillan
March 3, 2016

Study reveals possible ‘dimmer switch’ drug for Rett syndrome

Researchers at Vanderbilt University Medical Center have relieved symptoms in a mouse model of Rett syndrome with a drug-like compound that works like the dimmer switch in an electrical circuit.
By Bill Snyder
1 … 56 57 58 59 60 … 101