NIH

model of DNA double helix
July 30, 2015

Study sheds light on crucial DNA binding protein

Researchers at Vanderbilt University have established the molecular basis for the function of Replication Protein A (RPA), a DNA binding protein that is a crucial “scaffold” for genome replication, response to damage and repair.

By Bill Snyder
July 29, 2015

In a zebrafish’s eye

Vanderbilt investigators demonstrate that a certain eye lens protein is evolutionarily conserved between zebrafish and rat, suggesting that zebrafish can be used as a model system to understand eye lens disorders such as cataracts.

By Sanjay Mishra
July 27, 2015

Anticancer olive compounds

Compounds found in olives and olive oil have anticancer activity, which may contribute to the cancer preventive properties attributed to the Mediterranean diet.

By Leigh MacMillan
July 24, 2015

How to trick a wily virus

Vanderbilt investigators have discovered how human antibodies induced during testing of an experimental “bird flu” vaccine kill the virus.

By Sanjay Mishra
July 23, 2015

Targeting bone metastasis

The rigidity of the bone extracellular matrix increases the ability of tumor cells to destroy bone, suggesting new targets for anticancer drug development.

By VUMC News and Communications
July 23, 2015

Study explores protein’s role in inflammation-associated cancer

An antioxidant protein may protect against colon cancer that develops in patients with inflammatory bowel disease, suggesting new strategies for reducing colon cancer risk in these patients.

By Leigh MacMillan
July 15, 2015

Drug signaling networks

Vanderbilt investigators have developed a new algorithm to understand the networks of signaling molecules that control drug action.
By Leigh MacMillan
July 13, 2015

Hhex on cancer

A new mouse model demonstrates that the Hhex gene – which is linked to blood cancers – is critical for normal blood cell production.
By Henry H. Ong
July 10, 2015

Delivering cells for heart repair

A polymer hydrogel material developed by Vanderbilt scientists improved the delivery of stem cells for heart repair.
By Leigh MacMillan
June 25, 2015

Grant to spur study of ‘brown fat’s’ metabolic mysteries

Vanderbilt researchers have received a $2.15 million grant to study the amount and activity of “brown fat” in adults, with the aim of understanding its role in metabolic disease and identifying new therapeutic targets.
By VUMC News and Communications
June 16, 2015

A view of brain function in disease

Vanderbilt investigators report the first use of a specialized type of MRI to study the hippocampus in patients with schizophrenia.
By Leigh MacMillan
June 12, 2015

New strategy to combat HIV

Inhibitors of the enzyme phospholipase D1 suppress the replication of HIV-1, Vanderbilt investigators have discovered.
By Bill Snyder
June 11, 2015

A “CRISPR” way to study disease

Using revolutionary CRISPR technology, Vanderbilt investigators have developed a fast and simple method to simultaneously turn off multiple genes in order to study complex diseases.
By VUMC News and Communications
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