NIH

Anti-inflammatory protein “rheostat” sheds light on leaky blood vessels

Vanderbilt researchers have discovered that the protein CRADD counteracts inflammatory injury to endothelial cells, which could assist the development of new therapies for inflammatory vascular disorders.

New target for breast cancer therapy

The protein MTBP is overexpressed in an aggressive type of breast cancer, and it regulates another protein implicated in many cancer types, suggesting that it may be a good target for new therapeutics.

Natural killer cells don’t clear HMPV

Understanding how the immune system responds to the respiratory virus HMPV is crucial for developing vaccines and anti-viral treatments.

Reversing stress-induced anxiety

Augmenting the signals of natural “endocannabinoids” in the brain may be a promising approach for treating mood and anxiety disorders.

Neural receptor for reovirus

A newly identified receptor allows mammalian reovirus to infect neurons, shedding light on factors important for viral encephalitis.

Regulating immune regulators

Understanding how to control the generation of regulatory T cells could have important implications for treating autoimmunity and cancer.

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