NIMH

July 18, 2019

How proteins spread linked to Alzheimer’s disease sex differences

The ways certain proteins spread may help explain why the prevalence of Alzheimer’s is higher in women than in men.

By Kelsey Herbers
July 11, 2019

Working memory in psychotic disorders

Functional MRI studies have revealed that targeting activation of certain brain regions may improve working memory and cognition in psychotic disorders.

By Kelsey Herbers
June 24, 2019

Early detection of schizophrenia

Inhibited temperament — a tendency to respond to novelty with wariness, fear or caution — may be a risk factor for schizophrenia that could be targeted for preventative interventions.

By Leigh MacMillan
April 25, 2019

Immune ‘pruning’ in schizophrenia

Ariel Deutch and colleagues have discovered that overactive brain immune cells during adolescence may contribute to schizophrenia.

By Bill Snyder
April 24, 2019

Study merges big data and zebrafish biology to reveal mechanisms of human disease

In a series of studies that volleyed between large databases and research in zebrafish, Vanderbilt investigators have discovered a link between vascular biology and eye disease.

By Leigh MacMillan
March 28, 2019

Treatment resistance of mental disorders studied

With the aid of a four-year, $3.4 million grant from the National Institute of Mental Health, researchers at Vanderbilt University Medical Center and Massachusetts General Hospital (MGH) will apply new techniques to investigate treatment resistance of two devastating mental disorders — major depressive disorder, which befalls 15 percent of people at some point in their lives, and schizophrenia, which affects approximately 1 percent.

By Paul Govern
October 1, 2018

Cytokine-cognition connection

Targeting the immune system may provide a new avenue for therapeutic intervention in psychiatric diseases characterized by motivational and cognitive deficits.
By Laura Daniel
July 26, 2018

Vanderbilt study links gene expression, disease association data

An international team of researchers has integrated gene expression and disease association data to better understand the biological mechanisms of complex human diseases.
By Leigh MacMillan
March 9, 2018

Brain connections in schizophrenia

Brain imaging studies have implicated the connection between two brain regions in the pathophysiology of schizophrenia.
By Leigh MacMillan
December 19, 2017

Forming memories through CaMKII

Vanderbilt researchers have identified an interaction between two proteins that play a role in learning and memory.
By Sanjay Mishra
August 23, 2017

Oxidative stress on the brain

Vanderbilt investigators have discovered that oxidative damage may play an important role in the development of a rare cholesterol synthesis disease and in the behavioral changes of autism spectrum disorders.
By Sanjay Mishra
August 3, 2017

Researchers study unique couples intervention in Mozambique to reduce HIV transmission

Researchers in the Vanderbilt Institute for Global Health are testing whether a unique “couples-centered” intervention developed in the southern African nation of Mozambique can reduce mother-to-child transmission of HIV.
By Bill Snyder
April 28, 2017

Regulating anxiety in the brain

Two brain signaling pathways have overlapping functions in regulating anxiety, suggesting that therapeutics aimed at one or the other will impact both.
By Leigh MacMillan