NLM

Drug signaling networks

Vanderbilt investigators have developed a new algorithm to understand the networks of signaling molecules that control drug action.

Protein “pockets” help ID cancer genes

Vanderbilt investigators have used a computational biology approach to uncover new cancer drivers and biomarkers of anticancer drug response.

Drug discovery clues in network map

Vanderbilt investigators have constructed a network map that could guide the development of new targeted cancer therapies.

Web tool speeds pulmonary hypertension discovery

The pulmonary arterial hypertension knowledgebase (PAHKB), developed by Vanderbilt researchers, provides a useful tool for identifying PAH-related genes and signaling pathways relevant to pathogenesis.

Molecular circuits in ovarian cancer

Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer.

Tool helps plumb electronic records

A tool developed for one institution’s electronic health records can work at other institutions, potentially facilitating the use of these records in research studies.

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