pathology microbiology and immunology

array of test tubes with pipette dropping fluid into one

Destructive ‘telegrams’ in asthma

Vanderbilt investigators have discovered that certain microRNAs — “telegram”-like signals — increase after the induction of allergic airway inflammation.

Designing antibodies to fight the flu

Vanderbilt investigators said their work shows that computational design can improve the ability of naturally occurring antibodies to recognize different flu strains and may hasten the development of more effective flu therapies and vaccines.

white pills spilling out of a prescription bottle

Pain relievers a risk for C. diff?

A link between anti-inflammatory drugs such as ibuprofen and C. diff infection suggests caution against overusing such drugs in patients at high risk for infection.

RNA processing and antiviral immunity

John Karijolich and colleagues have discovered a link between cellular RNA processing and the innate cellular immune response to viral pathogens.

Discovery could lead to neutralizing West Nile virus

Researchers at Vanderbilt University Medical Center and colleagues have isolated a human monoclonal antibody that can “neutralize” the West Nile virus and potentially prevent a leading cause of viral encephalitis (brain inflammation) in the United States.

Team’s findings show glutamine metabolism affects T cell signaling

The cellular nutrient glutamine launches a metabolic signaling pathway that promotes the function of some immune system T cells and suppresses others, Vanderbilt researchers have discovered.

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