PET imaging

PET imaging probe for Alzheimer’s disease

Vanderbilt researchers report on a new PET imaging probe that will be useful for exploring Alzheimer’s disease pathology.

From left, Kimryn Rathmell, MD, PhD, Bradley Reinfeld, Matthew Madden and Jeffrey Rathmell, PhD, have discovered that immune cells — not cancer cells — are the major glucose consumers in the tumor microenvironment, upending a century-old observation.

Study revises understanding of cancer metabolism

Tumors consume glucose at high rates, but a team of Vanderbilt researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years.

Alzheimer’s proteins in ICU survivors

The cognitive impairment that affects patients who survive a stay in the ICU does not appear to have a similar mechanism to Alzheimer’s disease, Vanderbilt researchers have discovered.

PET imaging to predict tumor response

A PET probe that detects the amino acid glutamine predicts whether tumors respond to certain targeted therapies in preclinical animal models.

PET probe detects dying tumor cells

A novel PET imaging probe detects tumor cell death in vivo and could be useful for personalizing cancer medicine.