Reporter March 29 2019

March 28, 2019

Cancer’s SOS

Stephen Fesik and colleagues are advancing cancer drug discovery with the characterization of small molecules that modulate RAS, an important target for anti-cancer therapies.

By Sanjay Mishra
March 28, 2019

Cardiac dysfunction in DMD

The protein MMP7 is elevated in blood from patients with Duchenne muscular dystrophy who have cardiac dysfunction, suggesting that it may be a biomarker for heart disease severity.

By Leigh MacMillan
March 28, 2019

Drug interaction causes hypotension

A muscle relaxing-drug and inhibitors of the metabolic enzyme CYP1A2 interact to cause severely low blood pressure and should not be co-prescribed, Vanderbilt investigators caution.

By Leigh MacMillan
March 28, 2019

Unraveling endocytosis

New discoveries by Jason MacGurn and colleagues further understanding of the complex machinery that cells use take up substances from outside the cell.

By VUMC News and Communications
March 28, 2019

Treatment resistance of mental disorders studied

With the aid of a four-year, $3.4 million grant from the National Institute of Mental Health, researchers at Vanderbilt University Medical Center and Massachusetts General Hospital (MGH) will apply new techniques to investigate treatment resistance of two devastating mental disorders — major depressive disorder, which befalls 15 percent of people at some point in their lives, and schizophrenia, which affects approximately 1 percent.

By Paul Govern
March 28, 2019

Hot chemotherapy surgery helps save patient’s leg

Tom Deweese can keep up with his grandchildren because of a highly specialized surgery using hot chemotherapy that saved his leg.

By Tom Wilemon
March 28, 2019

SCRIPS Symposium

Speakers at the inaugural SCRIPS Spring Symposium (Supporting Careers in Research for Interventional Physicians and Surgeons) last week were, from left, Kelle Moley, MD, senior vice president and chief scientific officer of the March of Dimes; 2018 SCRIPS Scholars Yash Choksi, MD, and Akshitkumar Mistry, MD; and Anil Rustgi, MD.
March 28, 2019

Tool guides decision-making for prostate cancer patients

Prostate cancer patients in Nashville and Los Angeles are benefiting from a computer-based decision aid that implements the latest study results to tailor treatment options to an individual’s quality-of-life priorities.
By Craig Boerner
March 28, 2019

Vanderbilt Stallworth celebrates 25 years of service

Vanderbilt Stallworth Rehabilitation Hospital is celebrating its 25th anniversary.
By Holly Fletcher
March 28, 2019

Children’s after-hours clinic to open in Smyrna

Monroe Carell Jr. Children’s Hospital at Vanderbilt continues to lead the way in providing medical care closer to home with the opening of its sixth after-hours clinic in Smyrna on April 1.
By Jessica Pasley
March 28, 2019

Discovery Lecture

Ruth Lehmann, PhD, center, a world-renowned expert on the biology of germ cells, delivered last week’s Flexner Discovery Lecture.
By VUMC News and Communications
March 28, 2019

ACGME honors Moutsios’ contributions to teaching

The Accreditation Council for Graduate Medical Education (ACGME) recently presented awards to 29 recipients at its annual Educational Conference, recognizing noteworthy achievements from a wide range of talented graduate medical education professionals.
By Kathy Whitney
March 28, 2019

First artificial heart patient gets permanent replacement

Tim Lowell of Hernando, Mississippi, received the first total artificial heart in the state of Tennessee when the cardiac surgery team at Vanderbilt Health placed the device in his chest on Sept. 26, 2018. The mechanical heart kept him alive for nearly three months until a matching human donor heart became available and he was transplanted on Dec. 16, 2018, at Vanderbilt University Medical Center.
By Matt Batcheldor
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