Research

December 5, 2019

Study reveals mysteries of critical brain receptor complex

Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, Alzheimer’s disease, major depression and autism spectrum disorder. Understanding how AMPARs are formed and operate is essential for the rational design of pharmacological compounds that, by tuning AMPAR activity up or down, could improve treatment of these conditions.

By Bill Snyder
November 27, 2019

Study finds ‘frozen’ fear response may underlie PTSD

To explore how fear becomes entrenched, VUMC researchers traveled down the precise neuronal pathways in the brains of mice that trigger fear responses, and which normally extinguish the behaviors once the danger has passed.

By Bill Snyder
Max Joffe, PhD, left, P. Jeffrey Conn, PhD, and colleagues are studying a new class of antidepressants that may relieve symptoms more rapidly and with fewer side effects.
November 21, 2019

Study explores potential new class of antidepressants

Researchers at VUMC have taken a major step that could ultimately facilitate development of a new class of antidepressants which may relieve symptoms more rapidly and effectively and with fewer side effects than current medications.

By Bill Snyder
November 14, 2019

SPI-Hub resource delivers intel on biomedical journals

SPI-Hub, is a new online knowledge resource that gives biomedical scientists an efficient means to identify journals in which to publish their work.

By Paul Govern
Researchers on the NCI Moonshot grant focused on hereditary cancers include (front row, from left) Natasha Celaya-Cobbs, LPN, Georgia Wiesner, MD, Sarah Bland, MPH, MBA, (back row, from left) Trent Rosenbloom, MD, Josh Peterson, MD, MPH, and Marc Beller, PMP, BA.
November 14, 2019

NCI ‘Moonshot’ grant to boost hereditary cancer identification

VUMC is leading an initiative to establish a streamlined process for collection of family health histories that could set the stage for a standardized system to make the information easily accessible.

By Tom Wilemon
October 31, 2019

Vanderbilt investigators lead effort to create map of the human kidney

Short of mandating universal diabetes treatment, regular exercise and low-calorie diets, little can be done to stem the rising tide of kidney failure — unless scientists can figure out why exactly the kidney’s filtration units, the glomeruli, stop working.

By Bill Snyder
October 28, 2019

High fiber, yogurt diet associated with lower lung cancer risk

A diet high in fiber and yogurt is associated with a reduced risk for lung cancer, according to a study by Vanderbilt University Medical Center researchers.
By Tom Wilemon
October 24, 2019

Team set to study undiagnosed congenital diarrhea in infants

Researchers at four institutions, including Vanderbilt, have been awarded a five-year, $9.4 million federal grant to tackle undiagnosed congenital diarrheas caused by a single gene mutation.
By Christina Echegaray
October 17, 2019

Study finds men have higher mortality rate after breast cancer diagnosis

A new study shows men with breast cancer are more likely to die than their female counterparts, across all stages of disease.
By Tom Wilemon
October 10, 2019

Nobel laureate Südhof reviews his landmark signaling research

The human brain consists of perhaps as many as 1,000 trillion synapses, which transmit signals from one nerve cell to another with amazing speed, precision and plasticity.
By Bill Snyder
October 8, 2019

New leadership appointments for Pathology, Microbiology and Immunology

By Bill Snyder
October 3, 2019

Diabetes drug study explores cardiovascular risks for patients with kidney disease

An observational study using medical record information from nearly 50,000 U.S. military veterans sheds new light on which drugs are best for patients with Type 2 diabetes and one of its common complications, kidney disease.
By Paul Govern
September 25, 2019

Study shines light on architecture of kidney disease

A study of 280,000 U.S. veterans, including 56,000 African Americans, has identified in greater detail than ever before the genetic architecture of kidney function and chronic kidney disease (CKD), according to researchers at Vanderbilt University Medical Center and their colleagues.
By Bill Snyder
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