staph

June 2, 2022

Bacterial battle in 3D

Using imaging mass spectrometry and microscopy, Vanderbilt researchers visualized how staph bacteria modifies lipids in its membrane to evade immune system-mediated killing.

By Bill Snyder
January 27, 2022

Impaired neutrophils in autoimmunity

Vanderbilt researchers help answer the question of why patients with autoimmune diseases like lupus are more susceptible to bacterial infections: their neutrophils have impaired antibacterial activity.

By Leigh MacMillan
September 10, 2021

Caught in a web: study reveals that immune cells cooperate to trap and kill bacteria

Vanderbilt researchers have identified a new antibacterial mechanism that could inspire novel strategies for combating staph and other extracellular bacterial pathogens.

By Leigh MacMillan
June 9, 2020

Staph’s activation of blood clotting

Staph bacteria may change the factor they use to activate blood clotting — to evade the immune response — a new study suggests.

By Leigh MacMillan
October 31, 2019

Imaging host-pathogen battle for metal

An unprecedented view of bacterial products within infected tissues opens new opportunities to explore infection biology and devise novel therapeutic strategies.

By Leigh MacMillan
June 28, 2018

New staph virulence factor

Jun. 28, 2018—The new factor, an enzyme involved in host-pathogen interactions, may be a viable target for treating staph infections.

By Leigh MacMillan
September 21, 2017

Excess dietary manganese increases risk of staph infection in heart

Too much dietary manganese — an essential trace mineral found in leafy green vegetables, fruits and nuts — promotes infection of the heart by the bacterium Staphylococcus aureus (“staph”).
By Leigh MacMillan
August 6, 2015

Skaar receives American Asthma Foundation award

Eric Skaar, Ph.D., MPH, the Ernest W. Goodpasture Professor of Pathology, has received a Scholar Award from the American Asthma Foundation (AAF).
By Leigh MacMillan
December 4, 2014

Physician-scientist is dream job for Vanderbilt’s Cassat

Jim Cassat, M.D., Ph.D., a pediatric infectious disease specialist who joined the Vanderbilt faculty this summer, loves taking care of children with bone infections and doing research to understand the host-pathogen interactions during these invasive infections.
By Leigh MacMillan
October 16, 2014

Staph ‘gangs’ share nutrients during infection: study

Antibiotic-resistant bacteria can share resources to cause chronic infections, Vanderbilt investigators have discovered. The findings shed light on a long-standing question in infectious diseases and may inform new treatment strategies.
By Leigh MacMillan
March 3, 2014

Dismantling staph’s drug resistance

Targeting the enzyme FosB could make antibiotic-resistant staph bacteria sensitive to the antibiotic fosfomycin.
By Leigh MacMillan
June 20, 2013

Studies outline new model for staph bone infections

Osteomyelitis, a debilitating bone infection most frequently caused by Staphylococcus aureus (“staph”) bacteria, is particularly challenging to treat.
By Leigh MacMillan
February 21, 2013

Antibacterial protein’s molecular workings revealed

Vanderbilt investigators report new insights to the workings of calprotectin, an immune system protein that “starves” bacterial pathogens of the metal nutrients they require.
By Leigh MacMillan