Vanderbilt Center for Bone Biology

January 14, 2015

Inner ear keeps bones strong

Alterations of the vestibular system – the part of our inner ear that controls balance – may contribute to bone loss related to both aging and space travel.

By Matthew Correia
December 4, 2014

Physician-scientist is dream job for Vanderbilt’s Cassat

Jim Cassat, M.D., Ph.D., a pediatric infectious disease specialist who joined the Vanderbilt faculty this summer, loves taking care of children with bone infections and doing research to understand the host-pathogen interactions during these invasive infections.

By Leigh MacMillan
September 11, 2014

Bone healing therapy for NF1 fractures

A combination treatment delivered to the site of fractures may improve bone healing in patients with the genetic disease neurofibromatosis type-1.

By VUMC News and Communications
September 3, 2014

Aggressive bone cancers build more blood vessels

A subpopulation of bone cancer cells may be responsible for driving clinically aggressive behavior, suggesting new treatment options.

By Katherine Venmar
August 7, 2014

Novel treatment strengthens bones in genetic disease

An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.

By Leigh MacMillan
June 16, 2014

Factor impacts bone toughness

The factor ATF4 has a role in the toughness of bone and its resistance to fracture, suggesting new therapeutic targets.

By Leigh MacMillan
November 7, 2013

Neurotransmitter’s role in bone balance

Removal of the neurotransmitter norepinephrine from the space outside cells plays an important role in the regulation of bone remodeling.
By Leigh MacMillan
July 31, 2013

Factor’s role in long bone development

Insight into how the protein neurofibromin participates in the signaling pathway that produces the body’s long bones has implications for fracture healing in some patients.
By Leigh MacMillan
June 20, 2013

Studies outline new model for staph bone infections

Osteomyelitis, a debilitating bone infection most frequently caused by Staphylococcus aureus (“staph”) bacteria, is particularly challenging to treat.
By Leigh MacMillan
May 15, 2013

Inner ear’s role in bone remodeling

The inner ear system that senses gravity and movement plays a role in bone remodeling – a finding that has clinical implications for space travel and for patients with inner ear disorders.
By Leigh MacMillan
December 6, 2012

‘Longevity’ gene has role in bone loss

A gene associated with long life participates in the normal regulation of bone remodeling and may have a role in bone loss associated with aging.
By Leigh MacMillan
July 18, 2012

VU study finds stress fuels breast cancer metastasis to bone

Stress can promote breast cancer cell colonization of bone, Vanderbilt Center for Bone Biology investigators have discovered.
By Leigh MacMillan
November 18, 2011

Skeletal defects in genetic disorder

A new mouse model provides a tool for testing novel therapeutic approaches for neurofibromatosis.
By Leigh MacMillan