Vanderbilt Diabetes Research and Training Center

Marcela Brissova, PhD, and MD/PhD student John “Jack” Walker are part of the research team that developed a pseudoislet system for integrated studies of human islet function.

Pseudoislet system expected to advance pancreas and diabetes research

The multicellular, 3-D structure of human pancreatic islets — the areas of the pancreas containing hormone-producing or endocrine cells — has presented challenges to researchers as they study and manipulate these cells’ function, but Vanderbilt University Medical Center researchers have now developed a pseudoislet system that allows for much easier study of islet function.

Team members involved in the study include, from left, Melissa Hilmes, MD, Daniel Moore, MD, PhD, Alvin Powers, MD, Jon Williams, PhD, and Jack Virostko, PhD. (photo by Jessica Kimber)

Study expands insight on shrinking pancreas in type 1 diabetes

Researchers with the Vanderbilt Diabetes Research and Training Center (DRTC) have discovered a progressive decline in pancreas volume over a one-year period in children and adolescents with newly diagnosed Type 1 diabetes.

Evans set for next Discovery Lecture

Ronald Evans, PhD, renowned for his discoveries of nuclear hormone receptors and how they work, will deliver the next Flexner Discovery Lecture on Thursday, March 7.

First Islet Workshop draws international audience

More than 200 investigators from across the globe who specialize in islet biology, the study of hormone-producing cell clusters in the pancreas known as islets, recently gathered in Nashville to share knowledge and present the challenges and successes of their work during the first Islet Biology Workshop at Vanderbilt.

Diabetes Day

Research achievement was recognized recently during Diabetes Day at the Student Life Center. Among those honored were (beginning second from left) Bryan Gitschlag, Danielle Dean, PhD, Ian Williams, Caroline Presley, MD, and Suzanne Starr. Award winners are flanked by Tom Elasy, MD, MPH, (left) and Alvin Powers, MD. Diabetes Day was sponsored by the Vanderbilt Diabetes Research and Training Center and the Vanderbilt Center for Diabetes Translation Research and supported by the National Institutes of Health.

New phenotyping program to bolster global diabetes research efforts

The use of human pancreatic islets to conduct diabetes-related research has greatly expanded in recent years, and a Human Islet Phenotyping Program (HIPP) at Vanderbilt University Medical Center has been established to provide important islet data to investigators worldwide.

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