Although cancers arising from different areas of the large intestine are heterogeneous, they appear to use similar important tumorigenic pathways.

The elasticity of a scaffold used for healing skin wounds is a key factor in promoting regeneration versus scarring.

Drugs that inhibit the Wnt signaling pathway can regenerate injured skin and may be useful in treating fibromatosis, degenerative joint disease and cancer.

A signaling factor called Wnt10b is a novel target for optimizing cardiac repair after a heart attack.

Inhibitors of a signaling pathway that is critical to synovial sarcoma tumorigenesis may be useful treatments for this aggressive cancer.

Vanderbilt investigators used an in vivo screen in zebrafish to identify a potential new anti-cancer drug.

Enhancing stem cell survival is key to improving cell-based therapies for regenerative medicine, and a new drug could help.