May 29, 2009

Discovery Lecture to go to the nucleus of hormone receptors

Discovery Lecture to go to the nucleus of hormone receptors

Pierre Chambon, M.D., founder and former director of the Institute for Genetics and Cellular and Molecular Biology (IGBMC) and the Mouse Clinical Institute (ICS/MCI) in Strasbourg, France, will deliver the final Discovery Lecture of the spring semester.

Pierre Chambon, M.D.

Pierre Chambon, M.D.

The lecture, “Nuclear Receptors: From Mice to Diseases,” will be held at 4 p.m., Monday, June 8, in 208 Light Hall.

Chambon is one of the world's foremost experts in the field of gene structure and regulation, nuclear signal transduction and deciphering retinoic acid dependent pathways.

He shared the 2004 Lasker Basic Medical Research Award — sometimes referred to as the “American Nobel” prize — for the “discovery of the superfamily of nuclear hormone receptors and elucidation of a unifying mechanism that regulates embryonic development and diverse metabolic pathways.”

This work helped revolutionize the fields of endocrinology and metabolism and opened the possibility of new drug discovery strategies.

In addition to his numerous international prizes, Chambon is also a member of the French Académie des Sciences and a Foreign Member of the National Academy of Sciences (USA).

The lecture is sponsored by the Department of Cancer Biology.

For a complete schedule of the Discovery Lecture Series and archived video of previous lectures, go to www.mc.vanderbilt.edu/discoveryseries.