Genetics & Genomics

November 6, 2019

Study finds acid reducers may pose risk for children

The use of acid reducers among children is on the rise and so are potential side effects, which is sparking concern according to a recent study.

By Jessica Pasley
Adriana Hung, MD, MPH, talks with patient Sylvester Norman, who is participating in the VA Department’s Million Veteran Program.
September 25, 2019

Study shines light on architecture of kidney disease

A study of 280,000 U.S. veterans, including 56,000 African Americans, has identified in greater detail than ever before the genetic architecture of kidney function and chronic kidney disease (CKD), according to researchers at Vanderbilt University Medical Center and their colleagues.

By Bill Snyder
September 19, 2019

Gamazon receives NIH Genomic Innovator Award

VUMC’s Eric Gamazon is one of only six investigators to receive an inaugural Genomic Innovator Award from the National Human Genome Research Institute, part of the NIH.

By Leigh MacMillan
August 26, 2019

Cancer susceptibility genes

Gene variants associated with cancer risk appear to contribute to carcinogenesis by regulating target genes that in turn promote the generation of mutations.

By Leigh MacMillan
April 24, 2019

Study merges big data and zebrafish biology to reveal mechanisms of human disease

In a series of studies that volleyed between large databases and research in zebrafish, Vanderbilt investigators have discovered a link between vascular biology and eye disease.

By Leigh MacMillan
Researchers who helped find high-risk genes for schizophrenia included, from left, Quan Wang, PhD, Bingshan Li, PhD, Nancy Cox, PhD, Rui Chen, PhD, Xue Zhong, PhD, Qiang Wei, PhD, and James Sutcliffe, PhD.
April 18, 2019

Researchers find high-risk genes for schizophrenia

Using a unique computational framework they developed, a team of scientist cyber-sleuths in the Vanderbilt University Department of Molecular Physiology and Biophysics and the Vanderbilt Genetics Institute (VGI) has identified 104 high-risk genes for schizophrenia.

By Bill Snyder
January 31, 2019

Study explores genetic risk for suicide attempt

Using data from the UK Biobank and Vanderbilt’s BioVU, a new study in the journal Molecular Psychiatry finds that approximately 4 percent of suicide attempt risk is captured by genotype data.
By Paul Govern
December 31, 2018

Hundreds of new blood pressure gene variations discovered

By Bill Snyder
October 11, 2018

Novel genetic study sheds new light on risk of heart attack

Loss of a protein that regulates mitochondrial function can greatly increase the risk of myocardial infarction (heart attack), Vanderbilt scientists reported Oct. 3 in the journal eLife.
By Bill Snyder
October 1, 2018

Probing the genetics of fibroids

A new study identified multiple genetic locations associated with the size and number of uterine fibroids — common non-cancerous uterine tumors.
By Leigh MacMillan
July 26, 2018

Vanderbilt study links gene expression, disease association data

An international team of researchers has integrated gene expression and disease association data to better understand the biological mechanisms of complex human diseases.
By Leigh MacMillan
June 14, 2018

Shared genetics may shape treatment options for certain brain disorders

Symptoms of schizophrenia and bipolar disorder, including psychosis, depression and manic behavior, have both shared and distinguishing genetic factors, an international consortium led by researchers from Vanderbilt University and Virginia Commonwealth University is reporting.
By Bill Snyder
May 7, 2018

Study provides robust evidence of sex differences with Alzheimer’s gene

The APOE gene, the strongest genetic risk factor for Alzheimer’s disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer’s Center.
By Tom Wilemon
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