Genetics & Genomics

Researchers who helped find high-risk genes for schizophrenia included, from left, Quan Wang, PhD, Bingshan Li, PhD, Nancy Cox, PhD, Rui Chen, PhD, Xue Zhong, PhD, Qiang Wei, PhD, and James Sutcliffe, PhD.
April 18, 2019

Researchers find high-risk genes for schizophrenia

Using a unique computational framework they developed, a team of scientist cyber-sleuths in the Vanderbilt University Department of Molecular Physiology and Biophysics and the Vanderbilt Genetics Institute (VGI) has identified 104 high-risk genes for schizophrenia.

By Bill Snyder
January 31, 2019

Study explores genetic risk for suicide attempt

Using data from the UK Biobank and Vanderbilt’s BioVU, a new study in the journal Molecular Psychiatry finds that approximately 4 percent of suicide attempt risk is captured by genotype data.

By Paul Govern
December 31, 2018

Hundreds of new blood pressure gene variations discovered

By Bill Snyder
October 11, 2018

Novel genetic study sheds new light on risk of heart attack

Loss of a protein that regulates mitochondrial function can greatly increase the risk of myocardial infarction (heart attack), Vanderbilt scientists reported Oct. 3 in the journal eLife.

By Bill Snyder
October 1, 2018

Probing the genetics of fibroids

A new study identified multiple genetic locations associated with the size and number of uterine fibroids — common non-cancerous uterine tumors.

By Leigh MacMillan
July 26, 2018

Vanderbilt study links gene expression, disease association data

An international team of researchers has integrated gene expression and disease association data to better understand the biological mechanisms of complex human diseases.

By Leigh MacMillan
June 14, 2018

Shared genetics may shape treatment options for certain brain disorders

Symptoms of schizophrenia and bipolar disorder, including psychosis, depression and manic behavior, have both shared and distinguishing genetic factors, an international consortium led by researchers from Vanderbilt University and Virginia Commonwealth University is reporting.
By Bill Snyder
May 7, 2018

Study provides robust evidence of sex differences with Alzheimer’s gene

The APOE gene, the strongest genetic risk factor for Alzheimer’s disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer’s Center.
By Tom Wilemon
May 4, 2018

New breast cancer targets

A special genetic analysis has revealed candidate genes associated with increased risk of breast cancer.
By Bill Snyder
May 3, 2018

Gene study spots clues to heart risk for statin patients

A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol.
By Bill Snyder
January 25, 2018

Personalized drug prescribing program expands, upgrades

Vanderbilt University Medical Center (VUMC) has expanded and relaunched genetic testing to predict patient responses to drugs.
By Paul Govern
June 29, 2017

Genetics of lung cancer survival

Vanderbilt investigators have conducted a first-of-its-kind genome-wide association study of lung cancer survival in African-Americans.
By Sanjay Mishra
January 12, 2017

Investigators apply game theory to study of genomic privacy

It comes down to privacy — biomedical research can’t proceed without human genomic data sharing, and genomic data sharing can’t proceed without some reasonable level of assurance that de-identified data from patients and other research participants will stay de-identified after they’re released for research.
By Paul Govern
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