Infectious Diseases

tug-of-rope pair

VUMC investigators find pathogens work together to infect host

Pseudomonas aeruginosa and Staphylococcus aureus — two pathogens that frequently co-infect the lungs of patients with cystic fibrosis — appear to cooperate with each other, Vanderbilt investigators have discovered. When pseudomonas is starved for metal by the host, it shuts down the production of factors that would normally kill staph, promoting a co-infection.

zinc pill on spoon over white background

Study shows excess dietary zinc worsens C. diff infection

Too much dietary zinc increases susceptibility to infection by Clostridium difficile — “C. diff” — the most common cause of hospital-acquired infections.

drawing of trojan horse

Investigators create ‘Trojan Horse’ to fight Ebola

A multi-center research team including scientists from the Vanderbilt Vaccine Center has come up with a clever “Trojan Horse” strategy for thwarting the highly lethal Ebola virus.

Wright loves her patients and their mysteries

Everyone knew everyone in Patty Wright’s hometown of Scottsville, Kentucky, population 4,336.

Vanderbilt expert addresses Zika-related concerns for women who are, or want to become, pregnant

With summer time approaching and the topic of mosquitoes abuzz, Vanderbilt University Medical Center Maternal Fetal Medicine specialist Sarah Osmundson, M.D., has a few recommendations for women who are pregnant or want to become pregnant.

Detect and defend against pathogens

Understanding factors, such as the receptor TLR9, that detect and defend against pathogens may lead to therapeutic approaches that promote an effective immune response to treat infections.

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