Infectious Diseases Archive — Page 9 of 13
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March 18, 2021
HIV, diabetes and immune cells in fat
In HIV-positive individuals with diabetes, immune cells in fat are more proinflammatory and cytotoxic and may represent a therapeutic target for diabetes. -
February 8, 2021
Key factors in HIV-1 replication
HIV-1, the virus that causes AIDS, exploits inositol phosphates in T cells to aid its own assembly and maturation — suggesting that targeting inositol phosphate binding could inhibit HIV-1 replication. -
September 17, 2020
Probing pathogen antibiotic resistance
Understanding how bacteria evolve resistance to antibiotics and host stresses could guide the development of more effective antimicrobial therapeutics. -
June 10, 2020
C. diff captures blood cell cofactor to build defensive shield
Vanderbilt University Medical Center scientists have identified a C. diff protein system that senses and captures heme (part of hemoglobin) to build a protective shield that fends off threats from our immune system and antibiotics. -
June 3, 2020
Study explores how staph bacteria can survive in bone
A comprehensive evaluation of the metabolic pathways that support Staphylococcus aureus (“staph”) growth during invasive bone infections could offer new targets for treatment. -
May 14, 2020
The adaptable anthrax bacterium
Vanderbilt researchers discover how anthrax bacterium defends itself against structural damage and resists the toxicity of the antimicrobial drug targocil. -
February 6, 2020
Antibody mixture may help block Ebola virus infection
A research team led by scientists at Vanderbilt University Medical Center has developed an antibody mixture that in animals is highly effective in blocking infection by the Ebola virus.