acute kidney injury (AKI)

Raymond Harris, MD, left, and Ming-Zhi Zhang, MD, MSc, in the lab. (photo by John Russell)

VUMC discovery one step closer to treatment for kidney fibrosis

Study shows that deletion of EGFR from myeloid cells accelerated recovery from acute kidney injury and reduced subsequent fibrosis.

Study suggests possible stem-cell solution for acute kidney injury

Acute kidney injury is a sudden decrease in kidney function that can lead to kidney failure, the need for kidney dialysis and death.

High or low oxygen levels are safe during heart surgery: study

Two hundred study participants were assessed for oxidative stress, acute kidney injury, delirium, myocardial injury and atrial fibrillation.

Blood mutations increase risk for acute kidney injury: study

A U.S.-Canadian research collaboration led by Vanderbilt University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury, which occurs in more than 1 in 5 hospitalized adults worldwide.

By Bill Snyder

February 7, 2024

VUMC study finds molecular switch key to repair of kidney damage

Researchers at Vanderbilt University Medical Center have identified Rac1, a molecular switch that regulates the actin cytoskeleton of epithelial cells in the collecting ducts, as a driver of post-obstructive kidney repair.

By Bill Snyder

December 5, 2023

Role of immunity in kidney injury hints at a potential therapy: study

Targeting the cytokine IL-22 could be a new therapeutic approach to prevent kidney injury caused by drugs or toxins, Vanderbilt researchers have discovered.