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biovu Archives

Functional seizures associated with stroke, psychiatric disorders in electronic health records study

Jan. 7, 2021—In a large-scale study of electronic health records, Vanderbilt University Medical Center investigators have determined the prevalence of functional seizures and characterized comorbidities associated with them.

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New tool to probe genetic mechanisms of disease

Oct. 22, 2020—Vanderbilt Genetics Institute investigators have added a new method to the computational genetics toolbox. Their approach, described in the journal Nature Genetics, integrates vast genomics datasets to predict gene expression and facilitate discovery of genetic mechanisms underlying human diseases.

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Genes spell penicillin allergy risk

Oct. 1, 2020—Studies using large DNA biobanks revealed genetic variants associated with penicillin allergy, the most common type of drug-induced allergic reaction.

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Award supports integration of genomic data, electronic health records

Sep. 10, 2020—Eric Gamazon, PhD, assistant professor of Medicine, has been awarded a $1.5 million grant from the National Human Genome Research Institute, part of the National Institutes of Health (NIH), to develop novel computational tools that integrate functional genomic data and electronic health records.

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Kawai receives award to accelerate lupus research

Jul. 23, 2020—Vivian Kawai, MD, MPH, research assistant professor of Medicine, has received an LRA-BMS Accelerator Award from the Lupus Research Alliance and sponsoring partner Bristol Myers Squibb.

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EHRs, biobanks and Mendelian diseases

Apr. 30, 2020—Electronic health records and biobanks can be effectively combined to detect and study Mendelian diseases such as cystic fibrosis.

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VUMC joins global effort to explore COVID-19 genetics

Apr. 23, 2020—Vanderbilt University Medical Center investigators have joined an international genetics effort to make advances as quickly as possible on understanding and treating COVID-19.

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Vanderbilt-led team discovers new genetic disease and defines underlying mechanism

Jan. 13, 2020—An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms.

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Getting the goods on obesity

Nov. 19, 2019—Obesity and two post-operative complications linked with it have associated genetic variants in common, suggesting that obesity may be the culprit.

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Clinical study tests drug that may prevent cancer metastasis

Jul. 8, 2019—A clinical study of a drug that may block cancer metastasis is currently enrolling patients at the Vanderbilt-Ingram Cancer Center.

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Study merges big data and zebrafish biology to reveal mechanisms of human disease

Apr. 24, 2019—In a series of studies that volleyed between large databases and research in zebrafish, Vanderbilt investigators have discovered a link between vascular biology and eye disease.

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Study explores genetic risk for suicide attempt

Jan. 31, 2019—Using data from the UK Biobank and Vanderbilt’s BioVU, a new study in the journal Molecular Psychiatry finds that approximately 4 percent of suicide attempt risk is captured by genotype data.

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