biovu Archives
Codeine metabolizer status in clinical practice
Apr. 5, 2021—Vanderbilt researchers have developed a response score using genetic and clinical information to aid prescribing of the widely used pain medication codeine.
Roden honored with Oscar B. Hunter Career Award in Therapeutics
Mar. 15, 2021—Dan Roden, MD, Senior Vice President for Personalized Medicine at Vanderbilt University Medical Center, received the Oscar B. Hunter Career Award in Therapeutics last week at the virtual annual meeting of the American Society for Clinical Pharmacology and Therapeutics.
Electronic health record study discovers novel hormone deficiency
Mar. 11, 2021—A novel hormone deficiency may exist in humans, Vanderbilt investigators have discovered. In an analysis of two decades worth of electronic health records, the researchers found that some patients have unexpectedly low levels of natriuretic peptide hormone in clinical situations that should cause high levels of the hormone.
Functional seizures associated with stroke, psychiatric disorders in electronic health records study
Jan. 7, 2021—In a large-scale study of electronic health records, Vanderbilt University Medical Center investigators have determined the prevalence of functional seizures and characterized comorbidities associated with them.
New tool to probe genetic mechanisms of disease
Oct. 22, 2020—Vanderbilt Genetics Institute investigators have added a new method to the computational genetics toolbox. Their approach, described in the journal Nature Genetics, integrates vast genomics datasets to predict gene expression and facilitate discovery of genetic mechanisms underlying human diseases.
Genes spell penicillin allergy risk
Oct. 1, 2020—Studies using large DNA biobanks revealed genetic variants associated with penicillin allergy, the most common type of drug-induced allergic reaction.
Award supports integration of genomic data, electronic health records
Sep. 10, 2020—Eric Gamazon, PhD, assistant professor of Medicine, has been awarded a $1.5 million grant from the National Human Genome Research Institute, part of the National Institutes of Health (NIH), to develop novel computational tools that integrate functional genomic data and electronic health records.
Kawai receives award to accelerate lupus research
Jul. 23, 2020—Vivian Kawai, MD, MPH, research assistant professor of Medicine, has received an LRA-BMS Accelerator Award from the Lupus Research Alliance and sponsoring partner Bristol Myers Squibb.
EHRs, biobanks and Mendelian diseases
Apr. 30, 2020—Electronic health records and biobanks can be effectively combined to detect and study Mendelian diseases such as cystic fibrosis.
VUMC joins global effort to explore COVID-19 genetics
Apr. 23, 2020—Vanderbilt University Medical Center investigators have joined an international genetics effort to make advances as quickly as possible on understanding and treating COVID-19.
Vanderbilt-led team discovers new genetic disease and defines underlying mechanism
Jan. 13, 2020—An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms.
Getting the goods on obesity
Nov. 19, 2019—Obesity and two post-operative complications linked with it have associated genetic variants in common, suggesting that obesity may be the culprit.
