cardiovascular (heart) disease

The study found that chronically disrupted sleep and highly variable sleep durations night after night may increase the risk for atherosclerosis.
February 15, 2023

Study finds chronically disrupted sleep may increase risk for heart disease

Vanderbilt research found that sleep irregularity — chronically disrupted sleep and highly variable sleep durations night after night — may increase the risk for atherosclerosis.

By Bill Snyder
The research team included, from left, Hannah Poisner, Sydney Olson, J. Brett Heimlich, MD, PhD, Ningning Hu, MS, Alyssa Parker, Alexander Bick, MD, PhD, Joseph Van Amburg and Tara Mack.
February 2, 2023

Researchers clarify role of blood cell mutations in disease

Vanderbilt researchers have developed a new method to analyze mutations in blood stem cells that can trigger explosive, clonal expansions of abnormal cells.

By Bill Snyder
January 25, 2023

Study finds heart failure risk higher in rural areas

A study co-led by Vanderbilt researchers found heart failure risk is 19% higher for adults living in rural areas of the U.S., as compared to urban areas, and 34% higher for Black men living in rural areas.

By Craig Boerner
January 12, 2023

Study may lead to new diabetes, heart disease treatments

Vanderbilt research found that deletion of an autophagy-participating factor named PIK3C3 from the fat cells of mice led to compromised body temperature control, abnormal blood lipid levels, fatty liver and diabetes.

By Bill Snyder
December 15, 2022

Reduced kidney function may cause cardiovascular disease: study

An international team of investigators has found that mild to moderate reduction in kidney function may cause cardiovascular disease, even in people without symptoms of heart disease or diabetes.

By Bill Snyder
The study could suggest ways to promote the transport of phospholipids and cholesterol out of macrophages, immune system cells that play key roles in all stages of atherosclerosis development.
September 15, 2022

Study suggests new mechanism for lipid transporter

A new model suggests that a protein involved in the generation of high-density lipoprotein (HDL) works differently than previously thought.

By Leigh MacMillan
September 13, 2022

VUMC leads effort to map heart disease-causing genetic variations

Researchers from Vanderbilt University Medical Center, Stanford Medicine, the University of Toronto and Brigham and Women’s Hospital in Boston have joined forces to “map” the specific variations in more than 25 key cardiac disease genes that negatively affect heart function.
By Bill Snyder
August 17, 2022

Lindley named to direct new multidisciplinary Women’s Heart Center

Kathryn Lindley, MD, has joined the Vanderbilt Heart and Vascular Institute as director of the new Women’s Heart Center.
By Matt Batcheldor
July 13, 2022

Clinic offers ongoing care for pediatric heart patients

Vanderbilt recently launched a new multidisciplinary Fontan Clinic, which will provide an ongoing, coordinated care plan for children and teens, ages 10-19, who have had the Fontan procedure for single ventricle heart disease.
By Christina Echegaray
June 16, 2022

BMI genetics influence heart function

Vanderbilt researchers have discovered that a genetic predisposition to elevated body mass index increases the risk of diastolic dysfunction — a cardiac condition that can lead to heart failure.
By Leigh MacMillan
May 24, 2022

Diabetes, cardiovascular drug targets

Targeting receptors of the inflammatory lipid signaling molecule PGE2 may offer a new way to tackle both Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered.
By Leigh MacMillan
April 14, 2022

VUMC research team receives $1 million grant from AHA to study impact of long-COVID on heart

A research team led by Cyndya Shibao, MD, MSCI, associate professor of Medicine at Vanderbilt University Medical Center (VUMC), has received a three-year, $1-million grant from the American Heart Association to study long-term effects of COVID-19 on the heart and cardiovascular system.
By Bill Snyder
March 3, 2022

Chest Pain Center receives reaccreditation from ACC

Vanderbilt University Medical Center has been reaccredited as a Chest Pain Center with Primary Percutaneous Coronary Intervention (PCI) and Resuscitation.
By Kristin Smart
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