cardiovascular (heart) disease

The study could suggest ways to promote the transport of phospholipids and cholesterol out of macrophages, immune system cells that play key roles in all stages of atherosclerosis development.
September 15, 2022

Study suggests new mechanism for lipid transporter

A new model suggests that a protein involved in the generation of high-density lipoprotein (HDL) works differently than previously thought.

By Leigh MacMillan
September 13, 2022

VUMC leads effort to map heart disease-causing genetic variations

Researchers from Vanderbilt University Medical Center, Stanford Medicine, the University of Toronto and Brigham and Women’s Hospital in Boston have joined forces to “map” the specific variations in more than 25 key cardiac disease genes that negatively affect heart function.

By Bill Snyder
August 17, 2022

Lindley named to direct new multidisciplinary Women’s Heart Center

Kathryn Lindley, MD, has joined the Vanderbilt Heart and Vascular Institute as director of the new Women’s Heart Center.

By Matt Batcheldor
Heart patient Gabe Ezell, 11, recently visited Children’s Hospital’s new Fontan Clinic to check on his overall health in addition to his congenital heart condition. In the photo above, Gabe visits with Fontan team members Anita Pai, MD, left, and Angela Weingarten, MD.
July 13, 2022

Clinic offers ongoing care for pediatric heart patients

Vanderbilt recently launched a new multidisciplinary Fontan Clinic, which will provide an ongoing, coordinated care plan for children and teens, ages 10-19, who have had the Fontan procedure for single ventricle heart disease.

By Christina Echegaray
June 16, 2022

BMI genetics influence heart function

Vanderbilt researchers have discovered that a genetic predisposition to elevated body mass index increases the risk of diastolic dysfunction — a cardiac condition that can lead to heart failure.

By Leigh MacMillan
May 24, 2022

Diabetes, cardiovascular drug targets

Targeting receptors of the inflammatory lipid signaling molecule PGE2 may offer a new way to tackle both Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered.

By Leigh MacMillan
April 14, 2022

VUMC research team receives $1 million grant from AHA to study impact of long-COVID on heart

A research team led by Cyndya Shibao, MD, MSCI, associate professor of Medicine at Vanderbilt University Medical Center (VUMC), has received a three-year, $1-million grant from the American Heart Association to study long-term effects of COVID-19 on the heart and cardiovascular system.
By Bill Snyder
March 3, 2022

Chest Pain Center receives reaccreditation from ACC

Vanderbilt University Medical Center has been reaccredited as a Chest Pain Center with Primary Percutaneous Coronary Intervention (PCI) and Resuscitation.
By Kristin Smart
October 7, 2021

Study finds genetic testing useful for young AFib patients

Vanderbilt research shows that genetic testing in patients with early-onset atrial fibrillation can identify variants associated with more serious cardiomyopathy and arrhythmia syndromes that may otherwise remain undiagnosed.
By Matt Batcheldor
September 16, 2021

VUMC team to test personalized acute heart failure treatment

Researchers at Vanderbilt have been awarded a five-year, $4 million federal grant to test whether a personalized medicine strategy will improve outcomes for patients hospitalized with acute heart failure.
By Bill Snyder
August 19, 2021

Potential protection from atherosclerosis

Vanderbilt researchers have discovered a potential way to reduce atherosclerosis: blocking the modification of an HDL-associated enzyme by reactive molecules called isolevuglandins.
By Bill Snyder
August 12, 2021

Study reveals missing link between high-fat diet, microbiota and heart disease

A high-fat diet disrupts the biology of the gut’s inner lining and its microbial communities — and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science.
By Leigh MacMillan
July 8, 2021

Nature’s “recycler” could reduce heart disease risk: study

Researchers at Vanderbilt University Medical Center have identified potential new targets for the prevention of atherosclerosis through the enhancement of autophagy, a natural process for recycling damaged cellular material.
By Bill Snyder
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