Clostridioides difficile (C. diff)

March 22, 2018

Grant bolsters study of potential new therapy for C. diff infection

According to the Centers for Disease Control and Prevention, in 2011 in the United States there were almost half a million Clostridium difficile infections, and one in 11 patients 65 or older with a healthcare-associated C. diff infection died within 30 days of diagnosis.

By Paul Govern

Clostridium difficile bacterium, 3D illustration

January 26, 2018

Versatile C. difficile blocker

New research reveals a unique mechanism of C. difficile toxin neutralization by a monoclonal antibody, suggesting new therapeutic approaches.

By Bill Snyder

May 1, 2017

Clue to recurrent C. diff infection

Children who experience recurrent C. diff infections may have fecal inflammatory markers that could predict risk and improve management of these infections.

By Sanjay Mishra

zinc pill on spoon over white background

September 26, 2016

Study shows excess dietary zinc worsens C. diff infection

Too much dietary zinc increases susceptibility to infection by Clostridium difficile — “C. diff” — the most common cause of hospital-acquired infections.

By Leigh MacMillan

January 14, 2016

Crystal structure reveals secrets of virulent bacterium

Researchers at Vanderbilt University Medical Center have obtained the crystal structure of a toxin from the bacterium Clostridium difficile (“C. diff”) — the leading cause of hospital-acquired diarrhea in the United States.