Department of Cell and Developmental Biology

x-ray of stomach
January 16, 2020

VUMC study sheds light on gastric cancer development

VUMC researchers have created the world’s first laboratory model of precancerous changes in the lining of the stomach, a scientific tour de force that is helping to unlock the mysteries of gastric cancer development.

By Bill Snyder
January 13, 2020

Vanderbilt-led team discovers new genetic disease and defines underlying mechanism

An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms.

By Leigh MacMillan
Patrick Hu, MD, PhD, has been named assistant dean for Physician-Researcher Training and director of the Office for Medical Student Research.
December 4, 2019

Genetic screen in worms reveals critical step in insulin synthesis

The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes.

By Leigh MacMillan
From left, Qi Liu, PhD, Lori Coburn, MD, Gregor Neuert, PhD, Keith Wilson, MD, Ken Lau, PhD, and Bennett Landman, PhD, are leading VUMC’s contribution to the “gut cell atlas” program funded by the Leona M. and Harry B. Helmsley Charitable Trust.
November 20, 2019

Grant spurs effort to map biology of Crohn’s disease

VUMC has been awarded a three-year, $3 million grant to map — in unprecedented detail — the biology of Crohn’s disease.

By Bill Snyder
November 18, 2019

Understanding cell division

Vanderbilt researchers have uncovered another piece in the puzzle of how cells divide — a process that goes awry in cancer cells.

By Cayetana Arnaiz Yépez
November 14, 2019

VUMC researchers set for Cutting-Edge Discovery Lecture

Antiviral immunity, obesity and pulmonary fibrosis will be discussed by three Vanderbilt University researchers during a Cutting-Edge Discovery Lecture on Nov. 21. The lecture will begin at 4 p.m. in 208 Light Hall.

By Leigh MacMillan
October 24, 2019

Team set to study undiagnosed congenital diarrhea in infants

Researchers at four institutions, including Vanderbilt, have been awarded a five-year, $9.4 million federal grant to tackle undiagnosed congenital diarrheas caused by a single gene mutation.
By Christina Echegaray
October 17, 2019

Microscopic spines connect worm neurons

Worm neurons have microscopic “spines” — where nerve-to-nerve communication happens — that share features with mammalian neurons, supporting the use of worms to study spine genetics and biology.
By Leigh MacMillan
September 19, 2019

Microvilli in motion

Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border.
By Anivarya Kumar
September 5, 2019

The plus and minus of microtubules

Understanding the dynamic regulation of cytoskeletal microtubules may suggest new ways to treat disorders ranging from Alzheimer's disease to cancer.
By Bill Snyder
August 27, 2019

A “rheostat” for cancer signals

Jason MacGurn and colleagues have characterized a “rheostat” that sets WNT pathway signaling in breast cancer cells.
By Sanjay Mishra
August 15, 2019

Protein’s role in inflammation-related cancer studied

Investigators are exploring the molecular mechanisms behind the association of chronic inflammation and colon cancer.
By Tom Wilemon
August 12, 2019

Pancreatic cancer clue

Inflammation synergizes with a cell’s intrinsic genetic program to promote the development of pancreatic cancer.
By Niyati Vachharajani
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