Department of Cell and Developmental Biology

May 3, 2019

Researchers putting the brakes on lethal childhood cancer

Malignant rhabdoid tumor (MRT) is one of the most aggressive and lethal childhood cancers. Although rare — about 20 to 25 new cases are diagnosed annually in the United States — there is no standard effective treatment for the disease, which is driven by loss of an anti-cancer protein called SNF5. The chances are very small that a child will survive a year after MRT diagnosis.

By Bill Snyder
March 28, 2019

Unraveling endocytosis

New discoveries by Jason MacGurn and colleagues further understanding of the complex machinery that cells use take up substances from outside the cell.

By VUMC News and Communications
March 14, 2019

Germ cell biology expert Lehmann set for March 21 Discovery Lecture

Ruth Lehmann, PhD, a world-renowned expert on the biology of germ cells, which generate eggs and sperm, will deliver the next Flexner Discovery Lecture on Thursday, March 21.

By Bill Snyder
March 7, 2019

Vanderbilt mourns cancer researcher Stephen Hann

Stephen Hann, PhD, professor of Cell and Developmental Biology, died Feb. 27. He was 67.

By Leigh MacMillan
February 14, 2019

Adhesion protein optimizes border

Matthew Tyska and colleagues have found that an adhesion protein plays a key role in building the intestinal brush border that is essential for absorbing nutrients.

By Leigh MacMillan
January 31, 2019

New target for chronic kidney disease

Preventing the formation of secretory structures that promote scarring in the kidney could offer new therapeutic options for a disease that affects millions of people worldwide.

By Leigh MacMillan
January 31, 2019

Cell death pathway implicated in bone marrow failure

Vanderbilt investigators have linked a specific form of programmed cell death to myelodysplastic syndrome, a type of bone marrow failure.
By Leigh MacMillan
January 24, 2019

Vanderbilt Prize winner Amon to speak at Jan. 31 lecture

Angelika Amon, PhD, recipient of the 2018 Vanderbilt Prize in Biomedical Science, will deliver her Vanderbilt Prize lecture at 4 p.m. Thursday, Jan. 31, in 208 Light Hall.
By Bill Snyder
January 17, 2019

Building a pancreas

Vanderbilt investigators are defining the genetic programs that control the development of pancreatic beta cells — studies that could inform new cellular or regenerative therapies for diabetes.
By Leigh MacMillan
December 13, 2018

Breast cancer-killing RIG

A compound that activates a virus-sensing receptor has potent therapeutic effects in a mouse model of breast cancer.
By Leigh MacMillan
December 13, 2018

The exocyst dynamo

New methods have revealed details of vesicle trafficking in cells and are applicable to any protein complexes, potentially revolutionizing our understanding of cell dynamics.
By Bill Snyder
December 6, 2018

Team seeks to create gene expression map of worm’s nervous system

How do you build a brain? What “rules” govern where neurons end up, how they connect to each other, and which functions they perform?
By Leigh MacMillan
November 29, 2018

Analyzing single-cell landscapes

Vanderbilt researchers have developed a new tool for quantifying data from single-cell studies.
By Leigh MacMillan
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