Department of Cell and Developmental Biology

McLaughlin, Casagrande honored by the Society for Neuroscience

Two Vanderbilt University scientists — BethAnn McLaughlin, PhD, and the late Vivien Casagrande, PhD — have been honored by the Society for Neuroscience for making significant contributions to the advancement of women in science.

Lymphocytes attacking cancer cell

Evading cell death

Stress granules that form in response to cellular stress help cancer cells survive and develop resistance to treatment.

Novel genetic study sheds new light on risk of heart attack

Loss of a protein that regulates mitochondrial function can greatly increase the risk of myocardial infarction (heart attack), Vanderbilt scientists reported Oct. 3 in the journal eLife.

Cancer Moonshot award to help map tumor progression

A trans-institutional team of researchers at Vanderbilt University Medical Center and Vanderbilt University has received an $11 million Cancer Moonshot grant to build a single-cell resolution atlas to map out the routes that benign colonic polyps take to progress to colorectal cancer, the third most common cancer among both men and women in the United States.

How microvilli form

A protein called IRTKS helps build the microvilli that form the border of cells in the intestines, explaining why the protein is a frequent target of gut pathogens.

A brain-builder called “Shh”

New findings demonstrate a previously unappreciated role of Shh signaling activity in the proliferation of CGNPs — the presumed cell-of-origin for a subset of the malignant pediatric brain tumor medulloblastoma.

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