Department of Cell and Developmental Biology Archive — Page 7 of 13

Two white jigsaw puzzle pieces joined together, with a red heart spanning the seam, on a blue background.
June 10, 2019

Cell-cell signals in developing heart

Scott Baldwin and colleagues have discovered early signaling events during heart development, findings that could guide cell replacement therapies for heart disease.

White wireframe illustration of a human heart on a blue architectural blueprint grid.
May 9, 2019

Blueprint for rebuilding the heart

Young-Jae Nam and colleagues are discovering how to express specific factors in connective tissue cells to turn them into heart muscle cells.

Microscopic view of loosely arranged pink connective tissue with thin fibers and scattered dark purple cell nuclei.
May 9, 2019

The dynamic basement

Vanderbilt scientists led by Andrea Page-McCaw have discovered a new way to analyze repair of basement membranes — important structural and functional components of tissues.

Portrait of William Tansey, Ph.D., wearing glasses, a dark jacket, and a light blue collared shirt against a brown background.
May 3, 2019

Researchers putting the brakes on lethal childhood cancer

Malignant rhabdoid tumor (MRT) is one of the most aggressive and lethal childhood cancers. Although rare — about 20 to 25 new cases are diagnosed annually in the United States — there is no standard effective treatment for the disease, which is driven by loss of an anti-cancer protein called SNF5. The chances are very small that a child will survive a year after MRT diagnosis.

Colorized illustration of a eukaryotic cell showing a central nucleus, surrounding organelles, and layered membranes against a blurred cellular background.
March 28, 2019

Unraveling endocytosis

New discoveries by Jason MacGurn and colleagues further understanding of the complex machinery that cells use take up substances from outside the cell.

Black-and-white head-and-shoulders portrait illustration of Ruth Lehmann, PhD, smiling and wearing a dark high-collared top.
March 14, 2019

Germ cell biology expert Lehmann set for March 21 Discovery Lecture

Ruth Lehmann, PhD, a world-renowned expert on the biology of germ cells, which generate eggs and sperm, will deliver the next Flexner Discovery Lecture on Thursday, March 21.